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  1. Article

    Open Access

    Caesarean-section delivery and caries risk of 3-year-old Chinese children: a retrospective cohort study

    Caesarean-section (C-section) may influence children’s long-term health by affecting bacterial colonization. However, few studies have focused on the association between C-section delivery (CSD) and dental car...

    **n Ge, **aolin Lyu, Zhifei Zhou, Yang Mi, Tongqiang He, Buling Wu in BMC Oral Health (2023)

  2. Article

    Correction to: Sema3A Drives Alternative Macrophage Activation in the Resolution of Periodontitis via PI3K/AKT/mTOR Signaling

    Tian Tian, Leyi Chen, Ziting Wang, Mingqi Zhu, Wenan Xu, Buling Wu in Inflammation (2023)

  3. No Access

    Article

    Sema3A Drives Alternative Macrophage Activation in the Resolution of Periodontitis via PI3K/AKT/mTOR Signaling

    Macrophages actively participate in immunomodulatory processes throughout periodontal inflammation. Regulation of M1/M2 polarization affects macrophage chemokine and cytokine secretion, resulting in a distinct...

    Tian Tian, Leyi Chen, Ziting Wang, Mingqi Zhu, Wenan Xu, Buling Wu in Inflammation (2023)

  4. Article

    Open Access

    Establishment and validation of the autophagy-related ceRNA network in irreversible pulpitis

    The molecular mechanisms underlying the onset and progression of irreversible pulpitis have been studied for decades. Many studies have indicated a potential correlation between autophagy and this disease. Aga...

    Ye Wang, Qiuyan **e, Hongwen Yu, Bangyi Zhou, **aolan Guo, Buling Wu in BMC Genomics (2023)

  5. Article

    Open Access

    Genome-wide identification of potential odontogenic genes involved in the dental epithelium-mesenchymal interaction during early odontogenesis

    Epithelium-mesenchymal interactions are involved in odontogenic processes. Previous studies have focused on the intracellular signalling regulatory network in tooth development, but the functions of extracellu...

    Jiawen Chen, Tianyu Sun, Yan You, Binbin Lin, Buling Wu, **gyi Wu in BMC Genomics (2023)

  6. No Access

    Article

    Photobiomodulation activates undifferentiated macrophages and promotes M1/M2 macrophage polarization via PI3K/AKT/mTOR signaling pathway

    Macrophages are the main mediators of the inflammatory response and play a major role in the onset and maintenance of periodontitis. Studies revealed that photobiomodulation (PBM) can change the polarization s...

    Tian Tian, Ziting Wang, Leyi Chen, Wenan Xu, Buling Wu in Lasers in Medical Science (2023)

  7. Article

    Open Access

    A novel hypoxic lncRNA, HRL-SC, promotes the proliferation and migration of human dental pulp stem cells through the PI3K/AKT signaling pathway

    Human dental pulp stem cells (hDPSCs) are critical for pulp generation. hDPSCs proliferate faster under hypoxia, but the mechanism by which long noncoding RNA (lncRNA) regulates this process is not fully under...

    Junkai Zeng, Ming Chen, Yeqing Yang, Buling Wu in Stem Cell Research & Therapy (2022)

  8. Article

    Open Access

    Vertucci’s root canal configuration of 11,376 mandibular anteriors and its relationship with distolingual roots in mandibular first molars in a Cantonese population: a cone-beam computed tomography study

    Cone-beam computed tomography (CBCT) was used to study the root canal system of mandibular anteriors (MAs) in a Cantonese population and to evaluate the correlation between the complicated root canal configura...

    Yeqing Yang, Chong Jiang, Ming Chen, Junkai Zeng, Buling Wu in BMC Oral Health (2022)

  9. Article

    Correction to: An Overview of Mesenchymal Stem Cell‑based Therapy Mediated by Noncoding RNAs in the Treatment of Neurodegenerative Diseases

    Yifei Luo, Wei Qiu, Buling Wu, Fuchun Fang in Stem Cell Reviews and Reports (2022)

  10. No Access

    Article

    An Overview of Mesenchymal Stem Cell-based Therapy Mediated by Noncoding RNAs in the Treatment of Neurodegenerative Diseases

    Mesenchymal stem cells (MSCs) have become a promising tool for neurorestorative therapy of neurodegenerative diseases (NDDs), which are mainly characterized by the progressive and irreversible loss of neuronal...

    Yifei Luo, Wei Qiu, Buling Wu, Fuchun Fang in Stem Cell Reviews and Reports (2022)

  11. Article

    Open Access

    Comprehensive analysis of the long noncoding RNA-associated competitive endogenous RNA network in the osteogenic differentiation of periodontal ligament stem cells

    The mechanism implicated in the osteogenesis of human periodontal ligament stem cells (PDLSCs) has been investigated for years. Previous genomics data analyses showed that long noncoding RNA (lncRNA), microRNA...

    Lingzhi Lai, Zhaodan Wang, Yihong Ge, Wei Qiu, Buling Wu, Fuchun Fang in BMC Genomics (2022)

  12. Article

    Open Access

    Relationship between Chinese Baijiu consumption and dental caries among 55- to 74-year-old adults in Guangdong, southern China: a cross-sectional survey

    Whether an association between alcohol consumption and dental caries exists is still unclear. Chinese Baijiu is the most common alcohol consumed by middle-aged and elderly Chinese individuals. This study aimed...

    **angyu Huang, Yihao Liang, Weihua Fan, Wei Liu, Buling Wu, Jianbo Li in BMC Geriatrics (2021)

  13. Article

    Open Access

    Dynamic proteomic profiling of human periodontal ligament stem cells during osteogenic differentiation

    Human periodontal ligament stem cells (hPDLSCs) are ideal seed cells for periodontal regeneration. A greater understanding of the dynamic protein profiles during osteogenic differentiation contributed to the i...

    Jianjia Li, Zhifa Wang, **angyu Huang, Zhaodan Wang in Stem Cell Research & Therapy (2021)

  14. Article

    Open Access

    Classification and morphology of middle mesial canals of mandibular first molars in a southern Chinese subpopulation: a cone-beam computed tomographic study

    Cone-beam computed tomography (CBCT) was employed to study the morphology and curvature of middle mesial canals (MMCs) of mandibular first molars (MFMs).

    Yeqing Yang, Buling Wu, Junkai Zeng, Ming Chen in BMC Oral Health (2020)

  15. Article

    Open Access

    Diagnostic biomarker candidates for pulpitis revealed by bioinformatics analysis of merged microarray gene expression datasets

    Pulpitis is an inflammatory disease, the grade of which is classified according to the level of inflammation. Traditional methods of evaluating the status of dental pulp tissue in clinical practice have limita...

    Ming Chen, Junkai Zeng, Yeqing Yang, Buling Wu in BMC Oral Health (2020)

  16. Article

    Open Access

    Clinical efficacy of ceramic versus resin-based composite endocrowns in Chinese adults: study protocol for a randomized controlled trial

    Endocrown restoration is widely used to restore endodontically treated teeth. However, the clinical effects of different computer-aided design/computer-aided manufacturing (CAD/CAM) materials for endocrown res...

    Jilei Wang, Zhiting Ling, Ziting Zheng, Chunqing Zheng, Yawen Gai, Yuting Zeng in Trials (2020)

  17. Article

    Open Access

    Genome-wide identification of long noncoding RNAs and their competing endogenous RNA networks involved in the odontogenic differentiation of human dental pulp stem cells

    Long noncoding RNAs (lncRNAs) play an important role in the multiple differentiations of mesenchymal stem cells (MSCs). However, few studies have focused on the regulatory mechanism of lncRNAs in the odontogen...

    Zhao Chen, Kaiying Zhang, Wei Qiu, Yifei Luo, Yuhua Pan in Stem Cell Research & Therapy (2020)

  18. Article

    Open Access

    Magnesium-enriched microenvironment promotes odontogenic differentiation in human dental pulp stem cells by activating ERK/BMP2/Smads signaling

    Magnesium (Mg2+)-enriched microenvironment promotes odontogenic differentiation in human dental pulp stem cells (DPSCs), but the regulatory mechanisms remain undefined. The aim of this work was to assess magnesiu...

    Yuanyuan Kong, **aoli Hu, Yingqun Zhong, Ke Xu, Buling Wu in Stem Cell Research & Therapy (2019)

  19. Article

    Open Access

    Dual delivery of bone morphogenetic protein-2 and basic fibroblast growth factor from nanohydroxyapatite/collagen for bone tissue engineering

    In bone tissue engineering, the fabrication and biocompatibility of scaffold are crucial. Among many scaffold materials, nanohydroxyapatite (nHAP) and collagen (COL) are chosen as building materials of scaffol...

    Yuqian Hu, Linlin Zheng, **hui Zhang, Lijuan Lin, Yue Shen in Applied Biological Chemistry (2019)

  20. Article

    Open Access

    Noncoding RNAs: new insights into the odontogenic differentiation of dental tissue-derived mesenchymal stem cells

    Odontoblasts are cells that contribute to the formation of the dental pulp complex. The differentiation of dental tissue-derived mesenchymal stem cells into odontoblasts comprises many factors and signaling pa...

    Fuchun Fang, Kaiying Zhang, Zhao Chen, Buling Wu in Stem Cell Research & Therapy (2019)

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