6 Result(s)
within
Bruce F. O’Hara
Neurosciences
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Article
Open AccessNovel TNF receptor-1 inhibitors identified as potential therapeutic candidates for traumatic brain injury
Traumatic brain injury (TBI) begins with the application of mechanical force to the head or brain, which initiates systemic and cellular processes that are hallmarks of the disease. The pathological cascade of...
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Acute over-the-counter pharmacological intervention does not adversely affect behavioral outcome following diffuse traumatic brain injury in the mouse
Following mild traumatic brain injury (TBI), patients may self-treat symptoms of concussion, including post-traumatic headache, taking over-the-counter (OTC) analgesics. Administering one dose of OTC analgesic...
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Article
Open AccessMeditation acutely improves psychomotor vigilance, and may decrease sleep need
A number of benefits from meditation have been claimed by those who practice various traditions, but few have been well tested in scientifically controlled studies. Among these claims are improved performance ...
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Open AccessA non-circadian role for clock-genes in sleep homeostasis:a strain comparison
We have previously reported that the expression of circadian clock-genes increases in the cerebral cortex after sleep deprivation (SD) and that the sleep rebound following SD is attenuated in mice deficient fo...
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Free Communication Abstracts
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Article
Open AccessA role for cryptochromesin sleep regulation
The cryptochrome 1 and 2 genes (cry1 and cry2) are necessary for the generation of circadian rhythms, as mice lacking both of these genes (cry1,2-/-) lack circadian rhythms. We studied sleep in cry1,2-/- mice und...
