3 Result(s)
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Article
Open AccessNovel TNF receptor-1 inhibitors identified as potential therapeutic candidates for traumatic brain injury
Traumatic brain injury (TBI) begins with the application of mechanical force to the head or brain, which initiates systemic and cellular processes that are hallmarks of the disease. The pathological cascade of...
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Article
Open AccessA non-circadian role for clock-genes in sleep homeostasis:a strain comparison
We have previously reported that the expression of circadian clock-genes increases in the cerebral cortex after sleep deprivation (SD) and that the sleep rebound following SD is attenuated in mice deficient fo...
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Article
Open AccessA role for cryptochromesin sleep regulation
The cryptochrome 1 and 2 genes (cry1 and cry2) are necessary for the generation of circadian rhythms, as mice lacking both of these genes (cry1,2-/-) lack circadian rhythms. We studied sleep in cry1,2-/- mice und...
