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Article
Dose length product to effective dose coefficients in adults
The most accurate method for estimating patient effective dose (a principal metric for tracking patient radiation exposure) from computed tomography (CT) requires time-intensive Monte Carlo simulation. A simpl...
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Open AccessCorrection to: Dose length product to effective dose coefficients in children
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Open AccessDose length product to effective dose coefficients in children
The most accurate method for estimating effective dose (the most widely understood metric for tracking patient radiation exposure) from computed tomography (CT) requires time-intensive Monte Carlo simulation. ...
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Article
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Synovial sarcoma (SyS) is an aggressive neoplasm driven by the SS18–SSX fusion, and is characterized by low T cell infiltration. Here, we studied the cancer–immune interplay in SyS using an integrative approac...
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Open AccessTargetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models
T- and NK-cell lymphomas (TCL) are a heterogenous group of lymphoid malignancies with poor prognosis. In contrast to B-cell and myeloid malignancies, there are few preclinical models of TCLs, which has hampere...
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Open AccessCorrection: Corrigendum: Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival
Nature Communications 8 Article: 14013 (2017); Published 17 January 2017; Updated 14 August 2017 ‘In the References section of this Article, the citation listed as reference 17 is incorrect, and should have re...
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Open AccessContribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival
DNA repair gene defects are found in virtually all human glioblastomas, but the genetic evidence for a direct role remains lacking. Here we demonstrate that combined inactivation of the XRCC4 non-homologous end-j...
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Open AccessTranscriptome profiling of the dynamic life cycle of the scypohozoan jellyfish Aurelia aurita
The moon jellyfish Aurelia aurita is a widespread scyphozoan species that forms large seasonal blooms. Here we provide the first comprehensive view of the entire complex life of the Aurelia Red Sea strain by empl...
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Open AccessIllumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus
Chemical mutagenesis screens are useful to identify mutants involved in biological processes of interest. Identifying the mutation from such screens, however, often fails when using methodologies involving tra...
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Open AccessPremetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Sal**oeca rosetta
Metazoan multicellularity is rooted in mechanisms of cell adhesion, signaling, and differentiation that first evolved in the progenitors of metazoans. To reconstruct the genome composition of metazoan ancestor...
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Open AccessDe novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding RNAs
Accurate gene model predictions and annotation of alternative splicing events are imperative for genomic studies in organisms that contain genes with multiple exons. Currently most gene models for the intracel...
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Article
Open AccessGenome wide survey, discovery and evolution of repetitive elements in three Entamoeba species
Identification and map** of repetitive elements is a key step for accurate gene prediction and overall structural annotation of genomes. During the assembly and annotation of three highly repetitive amoeba g...
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Open AccessThe draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus)
In the early 1990s an outbreak of papaya ringspot virus (PRSV) in the papaya groves in the Puna district of Hawaii caused severe damage to an important crop. Since then, the planting of two transgenic cultivar...
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Correction: Corrigendum: Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
Nature 438, 1151–1156 (2005) There are two errors in the author listings for this Letter: the surname of Anne Lafon was misspelt as 'Lafton' and the affiliation of Hiroyuki Horiuchi should have been number 16 ...
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Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
More than 300 labs worldwide are using the fungus Aspergillus nidulans as a model system for molecular genetics, and other species of this fungus are important in everyday life. A package of three genomics papers...
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Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana
The genome of the flowering plant Arabidopsis thaliana has five chromosomes1,2. Here we report the sequence of the largest, chromosome 1, in two contigs of around 14.2 and 14.6 megabases. The contigs extend from ...
