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Article
Open AccessCtBP determines ovarian cancer cell fate through repression of death receptors
C-terminal binding protein 2 (CtBP2) is elevated in epithelial ovarian cancer, especially in the aggressive and highly lethal subtype, high-grade serous ovarian cancer (HGSOC). However, whether HGSOC tumor pro...
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Article
Open AccessSestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death
Sestrin2 is a member of a family of stress responsive proteins, which controls cell viability via antioxidant activity and regulation of the mammalian target of rapamycin protein kinase (mTOR). Sestrin2 is ind...