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  1. Article

    Open Access

    Reduction of contrast medium for transcatheter aortic valve replacement planning using a spectral detector CT: a prospective clinical trial

    This study investigated the use of dual-energy spectral detector computed tomography (CT) and virtual monoenergetic imaging (VMI) reconstructions in pre-interventional transcatheter aortic valve replacement (T...

    Isabel L. Langenbach, Marcel C. Langenbach, Thomas Mayrhofer in European Radiology (2024)

  2. Article

    Open Access

    Deep learning analysis of epicardial adipose tissue to predict cardiovascular risk in heavy smokers

    Heavy smokers are at increased risk for cardiovascular disease and may benefit from individualized risk quantification using routine lung cancer screening chest computed tomography. We investigated the prognos...

    Borek Foldyna, Ibrahim Hadzic, Roman Zeleznik in Communications Medicine (2024)

  3. Article

    Open Access

    Incidence of brain injuries in a large cohort of very preterm and extremely preterm infants at term-equivalent age: results of a single tertiary neonatal care center over 10 years

    Cerebral magnetic resonance imaging (cMRI) at term-equivalent age (TEA) can detect brain injury (BI) associated with adverse neurological outcomes in preterm infants. This study aimed to assess BI incidences i...

    Karla Drommelschmidt, Thomas Mayrhofer, Britta Hüning, Anja Stein in European Radiology (2024)

  4. Article

    Open Access

    Advanced CT measures of coronary artery disease with intermediate stenosis in patients with severe aortic valve stenosis

    Coronary artery disease (CAD) and severe aortic valve stenosis (AS) frequently coexist. While pre-transcatheter aortic valve replacement (TAVR) computed tomography angiography (CTA) allows to rule out obstruct...

    Marcel C. Langenbach, Isabel L. Langenbach, Borek Foldyna in European Radiology (2024)

  5. No Access

    Article

    Pulmonary perfusion defect volume on dual-energy CT: prognostic marker of adverse events in patients with suspected pulmonary embolism

    To assess whether quantification of pulmonary perfusion defects on dual-energy computed tomography (DECT) relates to adverse events beyond clinical parameters and traditional embolus detection in patients with...

    Borek Foldyna, Foroud Aghapour Zangeneh in The International Journal of Cardiovascula… (2023)

  6. No Access

    Article

    Prognostic value of CT-derived coronary artery disease characteristics varies by ASCVD risk: insights from the PROMISE trial

    To compare the prognostic value of individual CT-derived coronary artery disease (CAD) characteristics across categories of clinical cardiovascular risk.

    Borek Foldyna, Thomas Mayrhofer, Michael T. Lu, Júlia Karády in European Radiology (2023)

  7. No Access

    Article

    Quality and safety of coronary computed tomography angiography at academic and non-academic sites: insights from a large European registry (ESCR MR/CT Registry)

    To compare the use of coronary computed tomography angiography (CCTA) between academic and non-academic sites across Europe over the last decade.

    Borek Foldyna, Johannes Uhlig, Robin Gohmann, Christian Lücke in European Radiology (2022)

  8. No Access

    Article

    Small whole heart volume predicts cardiovascular events in patients with stable chest pain: insights from the PROMISE trial

    The size of the heart may predict major cardiovascular events (MACE) in patients with stable chest pain. We aimed to evaluate the prognostic value of 3D whole heart volume (WHV) derived from non-contrast cardi...

    Borek Foldyna, Roman Zeleznik, Parastou Eslami, Thomas Mayrhofer in European Radiology (2021)

  9. No Access

    Article

    Mid-term hemodynamic and functional results after transcatheter mitral valve leaflet repair with the new PASCAL device

    To examine the functional and hemodynamic mid-term outcome at 5 months of mitral regurgitation (MR) reduction using the PASCAL repair system.

    Sebastian Barth, Martina B. Hautmann, Eleni Arvaniti in Clinical Research in Cardiology (2021)

  10. Article

    Open Access

    Deep-learning system to improve the quality and efficiency of volumetric heart segmentation for breast cancer

    Although artificial intelligence algorithms are often developed and applied for narrow tasks, their implementation in other medical settings could help to improve patient care. Here we assess whether a deep-le...

    Roman Zeleznik, Jakob Weiss, Jana Taron, Christian Guthier in npj Digital Medicine (2021)

  11. Article

    Open Access

    Deep convolutional neural networks to predict cardiovascular risk from computed tomography

    Coronary artery calcium is an accurate predictor of cardiovascular events. While it is visible on all computed tomography (CT) scans of the chest, this information is not routinely quantified as it requires ex...

    Roman Zeleznik, Borek Foldyna, Parastou Eslami, Jakob Weiss in Nature Communications (2021)

  12. Article

    Open Access

    Quantitative coronary computed tomography angiography for the detection of cardiac allograft vasculopathy

    To associate coronary wall volume and composition, derived from coronary computed tomography angiography (CTA), with cardiac allograft vasculopathy (CAV) detected on invasive coronary angiography (ICA) in hear...

    Borek Foldyna, Marcus Sandri, Christian Luecke, Jens Garbade in European Radiology (2020)

  13. No Access

    Article

    Density and morphology of coronary artery calcium for the prediction of cardiovascular events: insights from the Framingham Heart Study

    To investigate the association between directly measured density and morphology of coronary artery calcium (CAC) with cardiovascular disease (CVD) events, using computed tomography (CT).

    Borek Foldyna, Parastou Eslami, Jan-Erik Scholtz in European Radiology (2019)

  14. No Access

    Article

    Computed tomography improves the differentiation of infectious mediastinitis from normal postoperative changes after sternotomy in cardiac surgery

    To identify CT parameters independently associated with infectious mediastinitis after cardiac surgery and to improve the discrimination of patients with acute infection from those with normal postoperative ch...

    Borek Foldyna, Martin Mueller, Christian D. Etz, Christian Luecke in European Radiology (2019)

  15. No Access

    Chapter

    Cardiac Computed Tomography

    During the last two decades, cardiac computed tomography (CT) has emerged as a routine procedure to investigate patients with cardiovascular issues and has revolutionized clinical practice. The rapid technical...

    Borek Foldyna, Michael Lu, Udo Hoffmann in Comprehensive Cardiovascular Medicine in t… (2019)

  16. No Access

    Article

    CAD-RADS – a new clinical decision support tool for coronary computed tomography angiography

    Coronary computed tomography angiography (CTA) has been established as an accurate method to non-invasively assess coronary artery disease (CAD). The proposed ‘Coronary Artery Disease Reporting and Data System...

    Borek Foldyna, Bálint Szilveszter, Jan-Erik Scholtz, Dahlia Banerji in European Radiology (2018)

  17. No Access

    Article

    Analysis of circumflex artery anatomy by real time 3D transesophageal echocardiography compared to cardiac computed tomography

    Iatrogenic injury to the circumflex artery (Cx) due to its close proximity to the mitral annulus is a rare but dreadful complication that can occur during mitral valve repair. The aim of our study was to compa...

    Carmine Bevilacqua, Sarah Eibel in The International Journal of Cardiovascula… (2017)

  18. No Access

    Article

    CT evaluation prior to transapical aortic valve replacement: semi-automatic versus manual image segmentation

    To compare the performance of semi-automatic versus manual segmentation for ECG-triggered cardiovascular computed tomography (CT) examinations prior to transcatheter aortic valve replacement (TAVR), with focus...

    Borek Foldyna, Camelia Jungert in The International Journal of Cardiovascula… (2015)

  19. Article

    Open Access

    Inter-individual variance and cardiac cycle dependency of aortic root dimensions and shape as assessed by ECG-gated multi-slice computed tomography in patients with severe aortic stenosis prior to transcatheter aortic valve implantation: is it crucial for correct sizing?

    To evaluate the inter-individual variance and the variability of the aortic root dimensions during the cardiac cycle by computed tomography (CT) in patients with severe aortic stenosis prior to transcatheter a...

    Lukas Lehmkuhl, Borek Foldyna in The International Journal of Cardiovascula… (2013)

  20. No Access

    Article

    Comparison of aortic root measurements in patients undergoing transapical aortic valve implantation (TA-AVI) using three-dimensional rotational angiography (3D-RA) and multislice computed tomography (MSCT): differences and variability

    To evaluate for the first time the degree of compliance between conventional multislice computed tomography (MSCT) and three-dimensional rotational angiography (3D-RA) in measuring relevant dimensions of the a...

    Lukas H. J. Lehmkuhl, Konstantin von Aspern in The International Journal of Cardiovascula… (2013)