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  1. Article

    Open Access

    Multi-perspective comparison of the immune microenvironment of primary colorectal cancer and liver metastases

    Liver metastases are a major contributor to the poor immunotherapy response in colorectal cancer patients. However, the distinctions in the immune microenvironment between primary tumors and liver metastases a...

    Yangsong He, Yanan Han, A-hui Fan, Danxiu Li… in Journal of Translational Medicine (2022)

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    Article

    A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens

    To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During ...

    Zhongyang Ding, Lianzhong Ai, Anran Ouyang… in European Food Research and Technology (2012)

  3. No Access

    Article

    Production and characterization of milk-clotting enzyme from Bacillus amyloliquefaciens JNU002 by submerged fermentation

    Milk-clotting enzymes produced by microorganisms have been developed to replace calf rennet, yet the enzymatic level and the ratio of milk-clotting activity to proteolytic activity still need further improveme...

    Zhongyang Ding, Wangfei Wang, Boda Wang… in European Food Research and Technology (2012)