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Book Series
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Chapter
Human African Trypanosomiasis (HAT)
Human African Trypanosomiasis (HAT) found only in sub-Saharan Africa is caused by the parasite Trypanosoma brucei, which is transmitted by tsetse flies. Only two sub-species of T. brucei are pathogenic for humans...
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Chapter
Drug Donation Programmes in the Control and Elimination of NTDs
This chapter reviews the history and evolution of the medicine donation model that has been the mainstay of neglected tropical disease (NTD) control programmes since Merck & Co., Inc. made the decision to dona...
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Book
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Chapter
Onchocerciasis Part I
Onchocerciasis, also known as river blindness, is a dermic filariasis caused by the nematode Onchocerca volvulus. The disease is found in 30 African countries between latitudes 15°N and 14°S. About 20.9 million p...
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Chapter
Onchocerciasis Part 2: Elimination
The International Task Force for Disease Eradication (ITFDE) defines elimination as the reduction to zero of the incidence of infection caused by a disease specific pathogen in a defined geographic area, as a ...
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Article
Open AccessMacrofilaricides and onchocerciasis control, mathematical modelling of the prospects for elimination
In most endemic parts of the world, onchocerciasis (river blindness) control relies, or will soon rely, exclusively on mass treatment with the microfilaricide ivermectin. Worldwide eradication of the parasite ...