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Network Pharmacology and Experimental Validation to Explore Mechanism of Tetrahydropalmatine on Acute Myocardial Ischemia

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  1. Article

    Open Access

    Radiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study

    Post-radiation nasopharyngeal necrosis (PRNN) is a severe adverse event following re-radiotherapy for patients with locally recurrent nasopharyngeal carcinoma (LRNPC) and associated with decreased survival. Bi...

    Ting Liu, Di Dong, Xun Zhao, **ao-Min Ou, Jun-Lin Yi, Jian Guan, Ye Zhang in BMC Medicine (2023)

  2. Article

    Open Access

    ASCL2 induces an immune excluded microenvironment by activating cancer-associated fibroblasts in microsatellite stable colorectal cancer

    Proficient mismatch repair or microsatellite stable (pMMR/MSS) colorectal cancers (CRCs) are vastly outnumbered by deficient mismatch repair or microsatellite instability-high (dMMR/MSI-H) tumors and lack a re...

    Dan Zhang, Qi-Qi Ni, Qiao-Yan Liang, Li-Ling He, Bo-Wen Qiu, Ling-Jie Zhang in Oncogene (2023)

  3. Article

    Open Access

    The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis

    Although accumulating evidence has highlighted the molecular mechanisms by which hTERT promotes tumour cell invasion and metastasis, the molecular mechanisms of the properties enabling hTERT to contribute to i...

    Yu-Yun Wu, Yu-Feng **ao, Li-**ng Tian, Bing He, Jiao Liu, Zhi-Bin Li, Huan Yang in Oncogene (2023)

  4. Article

    Open Access

    Spatio-temporal evolution and trend prediction of the incidence of Class B notifiable infectious diseases in China: a sample of statistical data from 2007 to 2020

    With the accelerated global integration and the impact of climatic, ecological and social environmental changes, China will continue to face the challenge of the outbreak and spread of emerging infectious dise...

    Ruo-Nan Wang, Yue-Chi Zhang, Bo-Tao Yu, Yan-Ting He, Bei Li in BMC Public Health (2022)

  5. Article

    Open Access

    Integrating single-cell RNA sequencing with spatial transcriptomics reveals immune landscape for interstitial cystitis

    Interstitial cystitis (IC) is a severely debilitating and chronic disorder with unclear etiology and pathophysiology, which makes the diagnosis difficult and treatment challenging. To investigate the role of i...

    Liao Peng, ** **, Bo-ya Li, **ao Zeng in Signal Transduction and Targeted Therapy (2022)

  6. Article

    Open Access

    Irinotecan plus temozolomide in relapsed Ewing sarcoma: an integrated analysis of retrospective studies

    The prognosis of patients with relapsed Ewing sarcoma is poor. In this study, we aimed to pooled-analyze the efficacy and safety of the combination of irinotecan and temozolomide in treating patients with rela...

    Bi-Cheng Wang, Bo-Ya **ao, Guo-He Lin in BMC Cancer (2022)

  7. Article

    Open Access

    Correction to: Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation

    Chuan-xia Zhang, Dai-jia Huang, Valentin Baloche, Lin Zhang, **g-xiao Xu in Oncogenesis (2022)

  8. Article

    Prolonged SARS-CoV-2 Viral Shedding in Patients with COVID-19 was Associated with Delayed Initiation of Arbidol Treatment and Consulting Doctor Later: A Retrospective Cohort Study

    To study data about SARS-CoV-2 virus shedding and clarify the risk factors for prolonged virus shedding.

    **n-liang He, Ya-ya Zhou, Wei Fu, Yu-e Xue, Meng-yuan Liang in Current Medical Science (2021)

  9. Article

    Open Access

    Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation

    Galectin-9 (Gal-9) is known to enhance the expansion of myeloid-derived suppressor cells (MDSCs) in murine models. Its contribution to the expansion of MDSCs in human malignancies remain to be investigated. We...

    Chuan-xia Zhang, Dai-jia Huang, Valentin Baloche, Lin Zhang, **g-xiao Xu in Oncogenesis (2020)

  10. Article

    Open Access

    The efficacy and safety of induction chemotherapy combined with concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in nasopharyngeal carcinoma patients: a systematic review and meta-analysis

    Induction chemotherapy (IC) combined with concurrent chemoradiotherapy (CCRT) has been recommended as the first-line therapy for locoregional nasopharyngeal carcinoma (NPC). Due to the different chemotherapeut...

    Bi-Cheng Wang, Bo-Ya **ao, Guo-He Lin, Chang Wang, Quentin Liu in BMC Cancer (2020)

  11. Article

    Open Access

    Unbiased screening reveals that blocking exportin 1 overcomes resistance to PI3Kα inhibition in breast cancer

    Xue-Ling Liu, Bo-Bo Wang, Yi Wang in Signal Transduction and Targeted Therapy (2019)

  12. Article

    Open Access

    Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma

    Extranodal natural killer T-cell lymphoma (nasal type; NKTCL) is an aggressive malignancy strongly associated with Epstein-Barr virus (EBV) infection. However, the role of EBV in NKTCL development is unclear, ...

    Rou-Jun Peng, Bo-Wei Han, Qing-Qing Cai, **ao-Yu Zuo, Tao **a, Jie-Rong Chen in Leukemia (2019)

  13. Article

    Open Access

    Associations of physical activity and fruit and vegetable intake with well-being and depressive symptoms among obese schoolchildren in Wuhan, China: a cross-sectional study

    The prevalence of childhood obesity is increasing and psychological disorder is a common comorbidity of obesity. We investigated the associations of physical activity (PA) and fruit and vegetable (FV) intake w...

    Hong-jie Yu, Fang Li, Yong-feng Hu, Chang-feng Li, Xu-hao Yang in BMC Public Health (2018)

  14. Article

    Open Access

    Dual-time-point myocardial 18F-FDG imaging in the detection of coronary artery disease

    Myocardial 18F-deoxyglucose (18F-FDG) uptake has been observed to be enhanced in patients with coronary artery disease (CAD) under fasting conditions. However, whether the increased 18F-FDG is induced by myocardi...

    Ke-Fei Dou, **ao-** Gao, Bo-Qia **e, Yan Li, Zuo-**ang He in BMC Cardiovascular Disorders (2017)

  15. Article

    Open Access

    Effect of acupuncture treatment on vascular cognitive impairment without dementia: study protocol for a randomized controlled trial

    Vascular cognitive impairment, no dementia (VCIND) is a condition at risk for future dementia and should be the target of preventive strategies. Preliminary evidence suggests that acupuncture may be a clinical...

    Bo-Feng Yang, **ang-Hong Zeng, Yan Liu, Qing-Nan Fu, Tian He, Fang Li in Trials (2014)

  16. Article

    Open Access

    Acupuncture at local and distal points for chronic shoulder pain: study protocol for a randomized controlled trial

    Chronic shoulder pain (CSP) is the third most common type of musculoskeletal pain. It has a major impact on health-related quality of life. In Chinese medicine, CSP is considered one of the conditions most ame...

    Qing-Nan Fu, Guang-**a Shi, Qian-Qian Li, Tian He, Bao-Zhen Liu, San-Feng Sun in Trials (2014)

  17. Article

    Open Access

    Clinical features and prognostic factors in patients with bone metastases from hepatocellular carcinoma after liver transplantation

    Little is known about the clinical features and prognostic factors of bone metastases of hepatocellular carcinoma (HCC) following liver transplantation (LT).

    Jian He, Zhao-Chong Zeng, Jia Fan, Jian Zhou, **g Sun, Bing Chen, ** Yang in BMC Cancer (2011)