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Open AccessIntegrating single-cell RNA sequencing with spatial transcriptomics reveals immune landscape for interstitial cystitis
Interstitial cystitis (IC) is a severely debilitating and chronic disorder with unclear etiology and pathophysiology, which makes the diagnosis difficult and treatment challenging. To investigate the role of i...
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Article
Open AccessIrinotecan plus temozolomide in relapsed Ewing sarcoma: an integrated analysis of retrospective studies
The prognosis of patients with relapsed Ewing sarcoma is poor. In this study, we aimed to pooled-analyze the efficacy and safety of the combination of irinotecan and temozolomide in treating patients with rela...
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Article
Open AccessThe efficacy and safety of induction chemotherapy combined with concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in nasopharyngeal carcinoma patients: a systematic review and meta-analysis
Induction chemotherapy (IC) combined with concurrent chemoradiotherapy (CCRT) has been recommended as the first-line therapy for locoregional nasopharyngeal carcinoma (NPC). Due to the different chemotherapeut...
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Article
Open AccessUnbiased screening reveals that blocking exportin 1 overcomes resistance to PI3Kα inhibition in breast cancer
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Article
Open AccessGenomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma
Extranodal natural killer T-cell lymphoma (nasal type; NKTCL) is an aggressive malignancy strongly associated with Epstein-Barr virus (EBV) infection. However, the role of EBV in NKTCL development is unclear, ...
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Article
Open AccessClinical features and prognostic factors in patients with bone metastases from hepatocellular carcinoma after liver transplantation
Little is known about the clinical features and prognostic factors of bone metastases of hepatocellular carcinoma (HCC) following liver transplantation (LT).