-
Article
Short-term outcomes of single-incision robotic colectomy versus conventional multiport laparoscopic colectomy for colon cancer
Since the da Vinci SP (dVSP) surgical system was introduced, single-incision robotic surgery (SIRS) for colorectal diseases has gained increasing acceptance. Comparison of the short-term outcomes between SIRS ...
-
Article
Open AccessOncologic relevance of genetic alterations in sporadic synchronous and solitary colorectal cancer: a retrospective multicenter study
Oncologic impact of genetic alteration across synchronous colorectal cancer (CRC) still remains unclear. This study aimed to compare the oncologic relevance according to genetic alteration between synchronous ...
-
Article
Open AccessLaparoscopic repair of perforated peptic ulcer: a multicenter, propensity score matching analysis
Perforated peptic ulcer (PPU) is a common emergency condition requiring surgery using laparoscopy or open repair of the perforated site. The aim of this study was to assess the role of laparoscopic surgery (LS...
-
Article
Clinical outcomes of laparoscopic versus open surgery for repairing colonoscopic perforation: a multicenter study
We conducted this study to compare the perioperative outcomes of laparoscopic surgery (LS) vs. open surgery (OS) for repairing colonoscopic perforation, and to evaluate the possible predictors of complications.
-
Article
Open AccessAnalysis of factors affecting reversal of Hartmann’s procedure and post-reversal complications
Although Hartmann’s procedure (HP) is commonly used as emergency treatment for colorectal disease, the reversal of HP (HR) is infrequently performed. The aims were to evaluate the rate of HR and determine the ...
-
Article
Clinical outcomes of sigmoid volvulus and risk factors for its recurrence: a multicenter study in Korea
Sigmoid volvulus is one of the leading causes of colonic obstruction. The aims of this study were to review the treatment characteristics and clinical outcomes of patients diagnosed with sigmoid volvulus over ...
-
Article
Open AccessThe FBW7-MCL-1 axis is key in M1 and M2 macrophage-related colon cancer cell progression: validating the immunotherapeutic value of targeting PI3Kγ
Colorectal cancer is a devastating disease with a low 5-year survival rate. Recently, many researchers have studied the mechanisms of tumor progression related to the tumor microenvironment. Here, we addressed...
-
Article
Open AccessIntratumor heterogeneity inferred from targeted deep sequencing as a prognostic indicator
Tumor genetic heterogeneity may underlie poor clinical outcomes because diverse subclones could be comprised of metastatic and drug resistant cells. Targeted deep sequencing has been used widely as a diagnosti...
-
Article
Oncologic outcome of colorectal cancer patients over age 80: a propensity score-matched analysis
It remains unclear whether old age is a poor prognostic factor in colorectal cancer (CRC). We compared oncologic outcomes in CRC patients according to age, using 80 as the dividing point.
-
Article
Open AccessPrevalence and detection of low-allele-fraction variants in clinical cancer samples
Accurate detection of genomic alterations using high-throughput sequencing is an essential component of precision cancer medicine. We characterize the variant allele fractions (VAFs) of somatic single nucleoti...
-
Article
Metformin enhances the response to radiotherapy in diabetic patients with rectal cancer
Metformin may have anticancer effects and could improve response to radiotherapy in several malignancies. We aimed to investigate the effect of metformin on response to radiotherapy in rectal cancer.
