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Article
Thermoresponsive and Biodegradable Amphiphilic Block Copolymers with Pendant Functional Groups
To develop the biodegradability and thermoresponsive hydrogel, in this work we designed a pendant-functionalized, thermoresponsive, amphiphilic block copolymer.
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Article
Open AccessBMP2-modified injectable hydrogel for osteogenic differentiation of human periodontal ligament stem cells
This is the first report on the development of a covalently bone morphogenetic protein-2 (BMP2)-immobilized hydrogel that is suitable for osteogenic differentiation of human periodontal ligament stem cells (hP...
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Article
Open AccessPreparation and investigation of hydrolyzed polyacrylonitrile as a preliminary biomedical hydrogel
Hydrolyzed polyacrylonitrile (HPAN) has attracted much attention as a hydrogel for a broad range of biomedical applications. Therefore, in this study, we prepared HPAN derivatives with controllable compositions b...
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Article
Preparation of methoxy poly (ethyleneglycol)-b-poly (ε-caprolactone-co-L-lactide) and characterization as biodegradable micelles
To compare methoxy poly (ethylene glycol) (MPEG)-b-poly (ε-caprolactone) (M7C10L0) and MPEG-b-poly (L-lactide) (M7C0L10), we performed block copolymerization of ε-caprolactone (CL) and L-lactide (LA) to synthesiz...
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Article
Chfr is linked to tumour metastasis through the downregulation of HDAC1
The ubiquitin ligase Chfr polyubiquitylates the histone deacetylase Hdac1, resulting in its proteolysis and the concomitant upregulation of metastasis suppressors, which may provide a molecular explanation for...
