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Anticancer potential and structure activity studies of purine and pyrimidine derivatives: an updated review
Cancer is the world’s leading cause of death impacting millions of lives globally. The increasing research over the past several decades has focused on the development of new anticancer drugs, but still cancer...
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Chapter
Fullerenes: Bucky Balls in the Therapeutic Application
In 1985, when Kroto found the third allotropic structure of carbon after diamond and graphite. A study on fullerene C60 began, and it has shown an increasing significance in biological research. Fullerenes were d...
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Molecular Docking and Cognitive Impairment Attenuating Effect of Phenolic Compound Rich Fraction of Trianthema portulacastrum in Scopolamine Induced Alzheimer’s Disease Like Condition
Dementia is considered as the frequent cause of neurodegenerative mental disorder such as Alzheimer’s disease (AD) amongst elderly people. Free radicals as well as cholinergic deficit neurons within nucleus ba...
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Article
Binding of anti-Trypanosoma natural products from African flora against selected drug targets: a docking study
Recent publications have suggested that African medicinal plants and their derived products could be viable source of new and better trypanocidal drugs. Nowadays, in silico methods are often used in drug disco...
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Article
Synthesis, biological evaluation, in silico docking, and virtual ADME studies of 2-[2-Oxo-3-(arylimino)indolin-1-yl]-N-arylacetamides as potent anti-breast cancer agents
A series of ten novel isatin analogs have been synthesized and screened for their in vitro anti-breast cancer activity against MCF-7 cell line using sulforhodamine-B assay method. All the tested compounds show...
