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Article
Open AccessHuman retinal endothelial cells express functional interleukin-6 receptor
Interleukin (IL)-6 is an inflammatory cytokine present in the eye during non-infectious uveitis, where it contributes to the progression of inflammation. There are two major IL-6 signaling pathways: classic si...
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Article
Genome-wide association study for sight-threatening diabetic retinopathy reveals association with genetic variation near the GRB2 gene
Diabetic retinopathy is a serious complication of diabetes mellitus and can lead to blindness. A genetic component, in addition to traditional risk factors, has been well described although strong genetic fact...
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Article
CD44 isoforms in human retinal and choroidal endothelial cells
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Article
Open AccessPrediction of cis-regulatory elements controlling genes differentially expressed by retinal and choroidal vascular endothelial cells
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Article
Open AccessPrediction of cis-regulatory elements controlling genes differentially expressed by retinal and choroidal vascular endothelial cells
Cultured endothelial cells of the human retina and choroid demonstrate distinct patterns of gene expression. We hypothesized that differential gene expression reflected differences in the interactions of trans...
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Article
A Novel H572R Mutation in the Transforming Growth Factor-β-Induced Gene in a Thai Family with Lattice Corneal Dystrophy Type I
To describe a large Thai family with lattice corneal dystrophy (LCD) type I and to determine whether this LCD is associated with mutations within the transforming growth factor-β-induced (TGFBI) gene.