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Open AccessFactors predicting resolution of left ventricular thrombus in different time windows after myocardial infarction
Left ventricular thrombus (LVT) is a serious complication after myocardial infarction. However, due to its asymptomatic nature, early detection is challenging. We aimed to explore the differences in clinical c...
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Article
Open AccessEfficacy and safety of antibiotics for treatment of leptospirosis: a systematic review and network meta-analysis
Leptospirosis, an important zoonotic bacterial disease, commonly affects resource-poor populations and results in significant morbidity and mortality worldwide. The value of antibiotics in leptospirosis remain...
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Open AccessREC8 regulates neuroblastoma cell proliferation, migration, invasion, and angiogenesis via STAT3/VEGF signaling
Neuroblastoma, one of the most prevalent childhood cancers, is often treated with surgery, radiation, and chemotherapy. However, prognosis and survival are still dismal for children with neuroblastoma at high ...
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Efficacy and safety of macrolides in the treatment of children with bronchiectasis: a meta-analysis
This study summarized the available randomized controlled trials (RCTs) to assess the efficacy and safety of macrolides on pathogens, lung function, laboratory parameters, and safety in children with bronchiec...
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Article
Living Arrangements and Subjective Well-Being of Elderly Chinese Tibetan People: The Mediating Role of Religion
While previous studies have found that living arrangements and religiosity can influence the subjective well-being (SWB) of older adults, they have tended to investigate each of these aspects separately. Engag...
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Open AccessStudy on the factors influencing the prognosis after perianal abscess surgery
To study the influence of clinical characteristics and diagnosis and treatment methods of perianal abscess on postoperative recurrence or formation of anal fistula to provide a basis for selecting appropriate ...
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Article
Open AccessImmediate and long-term outcomes after treat-all among people living with HIV in China: an interrupted time series analysis
In 2003, China implemented free antiretroviral therapy (ART) for people living with HIV (PLHIV), establishing an eligibility threshold of CD4 < 200 cells/μl. Subsequently, the entry criteria were revised in 20...
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Article
Bariatric surgery normalizes diabetes risk index by one month post-operation
The Diabetes risk index (DRI) is a composite of NMR-measured lipoproteins and branched chain amino acids predictive of diabetes mellitus development. Bariatric surgery is indicated in patients with severe obes...
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Article
Open AccessBone remodeling serum markers in children with systemic lupus erythematosus
SLE is an autoimmune multisystem disease. Glucocorticoid is an irreplaceable medication for SLE. Glucocorticoid and inflammatory mediators impact bone remodeling by OPG/RANKL/RANK signal system, which could le...
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Article
The Molecular Mechanisms of Cardiotoxicity Induced by HER2, VEGF, and Tyrosine Kinase Inhibitors: an Updated Review
In recent decades, there has been a revolutionary decrease in cancer-related mortality and an increase in survival due to the introduction of novel targeted drugs. Nevertheless, drugs targeting human epidermal...
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Article
Open AccessAssociations between new health conditions and healthcare service utilizations among older adults in the United Kingdom: effects of COVID-19 risks, worse financial situation, and lowered income
Health services are critically important for older adults, particularly during the Coronavirus disease-19 (COVID-19) pandemic. However, COVID-19 risks, worse financial situation, and lowered income may serious...
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Article
Open AccessAssociation between ethnicity and health knowledge among the floating population in China
Health equity remains a priority concerns by central government in China. This study aimed to explore ethnic gaps in access to health knowledge categories and sources based on the survey data from a publicly a...
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Article
KDM5B promotes cell migration by regulating the noncanonical Wnt/PCP pathway in Hirschsprung’s disease
We measured the expression of the histone demethylase lysine-specific demethylase 5B (KDM5B) in the bowels of patients with Hirschsprung’s disease (HSCR) and investigated the molecular mechanism by which KDM5B...
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Open AccessAntibiotic prophylaxis for prevention against Lyme disease following tick bite: an updated systematic review and meta-analysis
In areas where Lyme disease is endemic, bites from ticks are common, but no vaccine is currently available against Lyme disease for humans. Therefore, the feasibility of using antibiotic prophylaxis to prevent...
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Article
Open AccessAssociations between perceived environmental pollution and health-related quality of life in a Chinese adult population
Health-related quality of life (HRQoL) measures are being used in increasingly diverse populations. However, there have no known studies to date to examine the associations between perceived environmental poll...
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Open AccessAssociation between intestinal worm infection and malnutrition among rural children aged 9–11 years old in Guizhou Province, China
Intestinal worm infection adversely impacted child health and was one of the China’s largest health burdens. However, yet little was known about associations between intestinal worm infection and malnutrition ...
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Open AccessTai Chi Chuan in postsurgical non-small cell lung cancer patients: study protocol for a randomized controlled trial
Impairment of exercise capacity remains a common adverse effect of non-small cell lung cancer (NSCLC) survivors after surgery. Previous research has suggested that Tai Chi Chuan (TCC) offers an exercise capaci...
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Open AccessInfection by and genotype characteristics of Enterocytozoon bieneusi in HIV/AIDS patients from Guangxi Zhuang autonomous region, China
Enterocytozoon bieneusi has been increasingly reported to infect humans and various mammals. Microsporidia cause diarrhea in HIV-infected patients worldwide. PCR amplification and sequ...
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Open AccessRelationship between quality of life and unprotected anal intercourse among Chinese men who have sex with men: a cross-sectional study
The prevalence of unprotected anal intercourse (UAI) is high among Chinese men who have sex with men (MSM). As important aspects of quality of life (QOL), psychological health and social relationships have bee...
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High prevalence of cardiovascular risk factors in patients with moderate or severe psoriasis in northern China
Recent studies suggest that psoriasis is a systemic disorder associated with cardiovascular disease (CVD) risk factors, such as obesity, hypertension and dyslipidemia. However, these risk factors have not been...