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  1. Article

    Cytochrome P450 1A2 (CYP1A2) activity, mammographic density, and oxidative stress: a cross-sectional study

    Mammographically dense breast tissue is a strong predictor of breast cancer risk, and is influenced by both mitogens and mutagens. One enzyme that is able to affect both the mitogenic and mutagenic characteris...

    Chi-Chen Hong, Bing-Kou Tang, Venketeshwer Rao, Sanjiv Agarwal… in Breast Cancer Research (2004)

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  2. Article

    Cytochrome P450 1A2 (CYP1A2) activity and risk factors for breast cancer: a cross-sectional study

    Breast cancer risk may be determined by various genetic, metabolic, and lifestyle factors that alter sex hormone metabolism. Cytochrome P450 1A2 (CYP1A2) is responsible for the metabolism of estrogens and many...

    Chi-Chen Hong, Bing-Kou Tang, Geoffrey L Hammond, David Tritchler… in Breast Cancer Research (2004)

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    Article

    Multivariate cluster analysis of a human hepatic cytochrome P 450 database

    Sherwin K. Sy, James A. Johnston… in European Journal of Clinical Pharmacology (2002)

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    Article

    Modeling of human hepatic CYP3A4 enzyme kinetics, protein, and mRNA indicates deviation from log-normal distribution in CYP3A4 gene expression

    Abstract

    Sherwin K. Sy, Antonio Ciaccia, Wei Li… in European Journal of Clinical Pharmacology (2002)

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    Article

    Detailed characterization of experimentally derived human hepatic CYP1A1 activity and expression using differential inhibition of ethoxyresorufin O-deethylation by fluvoxamine

    Objective: To characterize the distribution of mathematically derived human hepatic CYP1A1 activity using differential inhibition of ethoxyresorufin O-deethylation (EROD) by fluvoxamine. Methods

    Sherwin K. Sy, Bing-Kou Tang… in European Journal of Clinical Pharmacology (2001)