63 Result(s)
within
Bin Han
Life Sciences
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Article
Computational tools for plant genomics and breeding
Plant genomics and crop breeding are at the intersection of biotechnology and information technology. Driven by a combination of high-throughput sequencing, molecular biology and data science, great advances h...
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Cutting the Gordian knot of plant genetics: retrieval of missing heritability in tomato
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Genotype calling and haplotype inference from low coverage sequence data in heterozygous plant genome using HetMap
This study developed a new genoty** method that can accurately infer heterozygous genotype information from the complex plant genome sequence data, which helped discover new alleles in the association studies.
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Open AccessSGSM2 inhibits thyroid cancer progression by activating RAP1 and enhancing competitive RAS inhibition
Thyroid cancer (TC) is one of the most common malignancies involving the head and neck, and its incidences are increasing every year. Small G protein signaling modulators 2 (SGSM2) belongs to a newly identifie...
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Open AccessHigh royal jelly production does not impact the gut microbiome of honey bees
Honey bees are not only essential for pollination services, but are also economically important as a source of hive products (e.g., honey, royal jelly, pollen, wax, and propolis) that are used as foods, cosmet...
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Open AccessIntegration of small RNAs, degradome, and transcriptome sequencing provides insights into the differences between Shizhu ginseng and Yuan ginseng
Panax ginseng is one of the most popular herbs which have been used as an important traditional Chinese medicine since ancient times. Yuan ginseng and Shizhu ginseng,which belong to P. ginseng, are widely used as...
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Open AccessOryzaGenome2.1: Database of Diverse Genotypes in Wild Oryza Species
OryzaGenome (http://viewer.shigen.info/oryzagenome21detail/index.xhtml), a feature within Oryzabase (https://shigen.nig.ac.jp/rice/oryzaba...
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Advances in genome-wide association studies of complex traits in rice
Genome-wide association studies (GWAS), genetic surveys of the whole genome to detect variants associated with a trait in natural populations, are a powerful approach for dissecting complex traits. This geneti...
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LncRNA GAS5-AS1 inhibits glioma proliferation, migration, and invasion via miR‐106b-5p/TUSC2 axis
Glioma is one of the most common malignant tumors and shows a high metastasis rate and poor prognosis. Abnormal expression of long non-coding RNAs (lncRNAs) contributes to various human tumors including glioma...
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Open AccessMiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer
The global morbidity and mortality of colorectal cancer (CRC) are ranked the third among gastrointestinal tumors in the world. MiR-451a is associated with several types of cancer, including CRC. However, the r...
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Open AccessDecreased IL-17RB expression impairs CD11b+CD11c− myeloid cell accumulation in gastric mucosa and host defense during the early-phase of Helicobacter pylori infection
Interleukin-17 receptor B (IL-17RB), a member of the IL-17 receptor family activated by IL-17B/IL-17E, has been shown to be involved in inflammatory diseases. However, the regulation and function of IL-17RB in He...
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Open AccessDegranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression
Mast cells are prominent components of solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, their precise mechanism of communication in gastric cancer remains largely unc...
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Open AccessCD45+CD33lowCD11bdim myeloid-derived suppressor cells suppress CD8+ T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer
Myeloid-derived suppressor cells (MDSCs) are a prominent component of the pro-tumoral response. The phenotype of and mechanisms used by MDSCs is heterogeneous and requires more precise characterization in gast...
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Study on immobilization of marine oil-degrading bacteria by carrier of algae materials
This study investigated the immobilizations with of bacteria two kinds of algal materials, Enteromorpha residue and kelp residue. The lipophilicity of them were compared by diesel absorption rates. The immobiliza...
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Open AccessMicrobial diversity and ecotoxicity of sediments 3 years after the Jiaozhou Bay oil spill
In 2013, the “Qingdao oil pipeline explosion” released an estimated 2000 tons of oil into the environment. Sediment samples were collected from ten sites in Jiaozhou Bay and Shilaoren Beach to evaluate the inf...
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Article
Sequence divergence between spelt and common wheat
Sequence comparison between spelt and common wheat reveals that the former has huge potential in enriching the genetic variation of the latter.
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Open AccessHelicobacter pylori-induced IL-33 modulates mast cell responses, benefits bacterial growth, and contributes to gastritis
Interleukin (IL)-induced inflammatory responses are critical for the pathogenesis of Helicobacter pylori (H. pylori)-induced gastritis. IL-33 represents a recently discovered proinflammatory cytokine involved in ...
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Genome-Wide Association Map** of Complex Traits in Rice
In rice varieties, there are many naturally occurring genetic variations. Most of morphological, developmental, and physiological variations in rice belong to complex quantitative traits controlled by dozens o...
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Open AccessQuorum sensing of microalgae associated marine Ponticoccus sp. PD-2 and its algicidal function regulation
Quorum sensing (QS) systems play important roles in regulating many physiological functions of microorganisms, such as biofilm formation, bioluminescence, and antibiotic production. One marine algicidal bacter...
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Open AccessGenomic insights into divergence and dual domestication of cultivated allotetraploid cottons
Cotton has been cultivated and used to make fabrics for at least 7000 years. Two allotetraploid species of great commercial importance, Gossypium hirsutum and Gossypium barbadense, were domesticated after polyplo...
