64 Result(s)

Article

Assessment of OCT-Based Macular Curvature and Its Relationship with Macular Microvasculature in Children with Anisomyopia

To evaluate the intraocular differences in optical coherence tomography (OCT)-based macular curvature index (MCI) among children with anisomyopia and to investigate the relationship between MCI and the macular...

Yue Wu, **n Liu, Yuying Liu, Wenzhe Qian, Liandi Huang… in Ophthalmology and Therapy (2024)

Article

Apolipoprotein O modulates cholesterol metabolism via NRF2/CYB5R3 independent of LDL receptor

Apolipoprotein O (APOO) plays a critical intracellular role in regulating lipid metabolism. Here, we investigated the roles of APOO in metabolism and atherogenesis in mice. Hepatic APOO expression was increase...

** Chen, Jiarui Hu, **n Guo, Yang Yang, Donglu Qin, **aoyu Tang… in Cell Death & Disease (2024)

Article

Integration of single-cell sequencing and bulk RNA-seq to identify and develop a prognostic signature related to colorectal cancer stem cells

The prognosis for patients with colorectal cancer (CRC) remains worse than expected due to metastasis, recurrence, and resistance to chemotherapy. Colorectal cancer stem cells (CRCSCs) play a vital role in tum...

Jiale Wu, Wanyu Li, Junyu Su, Jiamin Zheng, Yanwen Liang, Jiansuo Lin… in Scientific Reports (2024)

Article

A Composite Gene Polymorphism Signature for Preoperative Dexmedetomidine Sedation in Pediatrics: A Prospective Observational Study

Yan** Guan, Bilian Li, Siyi Wang, Wei Wei, Caibin Zhang… in Indian Journal of Pediatrics (2024)

Article

EP300-ZNF384 transactivates IL3RA to promote the progression of B-cell acute lymphoblastic leukemia

The EP300-ZNF384 fusion gene is an oncogenic driver in B-cell acute lymphoblastic leukemia (B-ALL). In the present study, we demonstrated that EP300-ZNF384 substantially induces the transcription of IL3RA and the...

Zhijie Hou, Yifei Ren, Xuehong Zhang, Dan Huang… in Cell Communication and Signaling (2024)

Article

High myopia is protective against diabetic retinopathy in the participants of the National Health and Nutrition Examination Survey

To investigate the association of subjects with refractive error and diabetic retinopathy (DR) in the United States comparing results between different race groups.

Weijung Ten, Ying Yuan, Wei Zhang, Yue Wu, Bilian Ke in BMC Ophthalmology (2023)

Article

Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness

Cancer cell receives extracellular signal inputs to obtain a stem-like status, yet how tumor microenvironmental (TME) neural signals steer cancer stemness to establish the hierarchical tumor architectures remains...

Bin He, Rui Gao, Shasha Lv, Ailin Chen… in Signal Transduction and Targeted Therapy (2023)

Article

Discovering a cohesive football team through players’ attributed collaboration networks

The process of team composition in multiplayer sports such as football has been a main area of interest within the field of the science of teamwork, which is important for improving competition results and gam...

Shenbao Yu, Yifeng Zeng, Yinghui Pan, Bilian Chen in Applied Intelligence (2023)

Article

Whole genome sequencing and analysis of Armillaria gallica Jzi34 symbiotic with Gastrodia elata

Armillaria species are plant pathogens, but a few Armillaria species can establish a symbiotic relationship with Gastrodia elata, a rootless and leafless orchid, that is used as a Chinese herbal medicine. Armill...

**long Cai, Ikram Muhammad, Bilian Chen, Peng Xu, Yiguo Li, Huini Xu… in BMC Genomics (2023)

Article

MedMNIST v2 - A large-scale lightweight benchmark for 2D and 3D biomedical image classification

We introduce MedMNIST v2, a large-scale MNIST-like dataset collection of standardized biomedical images, including 12 datasets for 2D and 6 datasets for 3D. All images are pre-processed into a small size of 28 × ...

Jiancheng Yang, Rui Shi, Donglai Wei, Zequan Liu, Lin Zhao, Bilian Ke… in Scientific Data (2023)

Article

miR-182-5p promotes hepatocyte-stellate cell crosstalk to facilitate liver regeneration

A unique feature of the liver is its high regenerative capacity, which is essential to maintain liver homeostasis. However, key regulators of liver regeneration (LR) remain ill-defined. Here, we identify hepat...

Ting **ao, Wen Meng, Zhangliu **, **g Wang, Jiangming Deng… in Communications Biology (2022)

Article

Sp1 induced gene TIMP1 is related to immune cell infiltration in glioblastoma

Tumor immune microenvironment exerts a profound effect on the population of infiltrating immune cells. Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) is frequently overexpressed in a variety of cells, ...

Lu Liu, Shuyao Yang, Kefeng Lin, **aoman Yu, Jiaqi Meng, Chao Ma… in Scientific Reports (2022)

Article

Nuclear Aurora kinase A switches m⁶A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4

Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression, yet how this process is regulated by oncogenic signal remains largely unknown. Here, we unveil that non-canonical a...

SiSi Li, YangFan Qi, JiaChuan Yu, YuChao Hao… in Signal Transduction and Targeted Therapy (2022)