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Article
Open AccessA rehabilitation intervention to improve recovery after an episode of delirium in adults over 65 years (RecoverED): study protocol for a multi-centre, single-arm feasibility study
Delirium affects over 20% of all hospitalised older adults. Delirium is associated with a number of adverse outcomes following hospital admission including cognitive decline, anxiety and depression, increased ...
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Article
Open AccessUterine sarcoma: almost more tumor than patient
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Article
Open AccessInvestigation of the Factor Structure and Differential Item Functioning of the Child and Adolescent Mindfulness Measure (CAMM): Analysis of Data from a School-Based Cluster Randomised Controlled Trial
This study used data from a randomised controlled trial of a school-based mindfulness programme in the UK to investigate the structure and performance of the 10-item Child and Adolescent Mindfulness Measure (C...
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Article
Open AccessThe P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection
The mutational landscape of SARS-CoV-2 varies at the dominant viral genome sequence and minor genomic variant population. During the COVID-19 pandemic, an early substitution in the genome was the D614G change ...
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Article
Open AccessSpatio-temporal statistical analysis of PM1 and PM2.5 concentrations and their key influencing factors at Guayaquil city, Ecuador
Guayaquil, Ecuador, is in a tropical area on the equatorial Pacific Ocean coast of South America. Since 2008 the city has been increasing its population, vehicle fleet and manufacturing industries. Within the ...
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Air Quality in Latin American Buildings
The air people breathe has a significant impact on their health, comfort, productivity, and well-being. Indoor air is important because it is where most exposure to airborne contaminants occurs. However, it is...
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Article
Open AccessPM2.5 exceedances and source appointment as inputs for an early warning system
Between June 2018 and April 2019, a sampling campaign was carried out to collect PM2.5, monitoring meteorological parameters and anthropogenic events in the Sartenejas Valley, Venezuela. We develop a logistic mod...
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Article
Open AccessShould RECOVERY have used response adaptive randomisation? Evidence from a simulation study
The Randomised Evaluation of COVID-19 Therapy (RECOVERY) trial is aimed at addressing the urgent need to find effective treatments for patients hospitalised with suspected or confirmed COVID-19. The trial has ...
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Article
Open AccessMinimising young children’s anxiety through schools (MY-CATS): protocol for a cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of an online parent-led intervention compared with usual school practice for young children identified as at risk for anxiety disorders
Identifying and supporting young children who are at risk of develo** anxiety disorders would benefit children, families, and wider society. Elevated anxiety symptoms, inhibited temperament, and high parenta...
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Article
Open AccessCorrection to: Quality assessment with diverse studies (QuADS): an appraisal tool for methodological and reporting quality in systematic reviews of mixed- or multimethod studies
An amendment to this paper has been published and can be accessed via the original article.
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Article
Capillary stop valve actuation by thermo-pneumatic- pressure for lab-on-chip systems
A novel method is presented for triggering a robust capillary stop valve fabricated in silicon using the thermal expansion of trapped air bubble (with a footprint of just 300 μm × 320 μm) as the actuation elem...
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Article
Open AccessQuality assessment with diverse studies (QuADS): an appraisal tool for methodological and reporting quality in systematic reviews of mixed- or multi-method studies
In the context of the volume of mixed- and multi-methods studies in health services research, the present study sought to develop an appraisal tool to determine the methodological and reporting quality of such...
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Article
Open AccessSeldom heard voices: a meta-narrative systematic review of Aboriginal and Torres Strait Islander peoples healthcare experiences
It is well established that Aboriginal and Torres Strait Islander populations face considerable health inequities, exacerbated by poorer healthcare quality. Patient experience is recognised as a major contribu...
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Article
Open AccessDisruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype
The clinically important MAM blood group antigen is present on haematopoietic cells of all humans except rare MAM-negative individuals. Its molecular basis is unknown. By whole-exome sequencing we identify EMP3, ...
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Article
Open AccessQuantitative spatio-temporal characterization of epileptic spikes using high density EEG: Differences between NREM sleep and REM sleep
In this study, we applied high-density EEG recordings (HD-EEG) to quantitatively characterize the fine-grained spatiotemporal distribution of inter-ictal epileptiform discharges (IEDs) across different sleep s...
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Article
Phase 1b trial of nintedanib in combination with bevacizumab in patients with advanced solid tumors
Vascular endothelial growth factor (VEGF) inhibitors have produced demonstrable but limited benefit for various cancers. One mechanism of resistance includes revascularization, secondary to upregulation of alt...
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Article
Open Access21st-century modeled permafrost carbon emissions accelerated by abrupt thaw beneath lakes
Permafrost carbon feedback (PCF) modeling has focused on gradual thaw of near-surface permafrost leading to enhanced carbon dioxide and methane emissions that accelerate global climate warming. These state-of-...
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Article
Open AccessWavelength-shifting properties of luminescence nanoparticles for high energy particle detection and specific physics process observation
Ultraviolet (UV) photon detection is becoming increasingly important in the quest to understand the fundamental building blocks of our universe. Basic properties of neutrinos and Dark Matter are currently bein...
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Article
When outbound mobility programs and service learning align in pre-service teacher education
This project sought to investigate the learning that comes about from the intersection of outbound mobility experience programs (OMEs) with service learning in pre-service teacher education settings. The aim o...
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Article
A valveless capillary mixing system using a novel approach for passive flow control
Using capillary-driven forces as a means to pump and actuate fluids is attractive for many applications including portable, lab-on-a-chip diagnostic systems. However, the lack of reliable and easy-to-integrate...
