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    Chapter

    Perfringolysin O Structure and Mechanism of Pore Formation as a Paradigm for Cholesterol-Dependent Cytolysins

    Cholesterol-dependent cytolysins (CDCs) constitute a family of pore forming toxins secreted by Gram-positive bacteria. These toxins form transmembrane pores by inserting a large β-barrel into cholesterol-conta...

    Benjamin B. Johnson, Alejandro P. Heuck in MACPF/CDC Proteins - Agents of Defence, At… (2014)