5 Result(s)
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Article
Open AccessHighly-accurate metabolomic detection of early-stage ovarian cancer
High performance mass spectrometry was employed to interrogate the serum metabolome of early-stage ovarian cancer (OC) patients and age-matched control women. The resulting spectral features were used to estab...
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Article
Open AccessEvidence for the importance of post-transcriptional regulatory changes in ovarian cancer progression and the contribution of miRNAs
High-throughput technologies have identified significant changes in patterns of mRNA expression over cancer development but the functional significance of these changes often rests upon the assumption that obs...
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Article
Open AccessMachine learning predicts individual cancer patient responses to therapeutic drugs with high accuracy
Precision or personalized cancer medicine is a clinical approach that strives to customize therapies based upon the genomic profiles of individual patient tumors. Machine learning (ML) is a computational metho...
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Article
Open AccessLabel-free microfluidic enrichment of cancer cells from non-cancer cells in ascites
The isolation of a patient's metastatic cancer cells is the first, enabling step toward treatment of that patient using modern personalized medicine techniques. Whereas traditional standard-of-care approaches ...
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Article
Open AccessHigh throughput, label-free isolation of circulating tumor cell clusters in meshed microwells
Extremely rare circulating tumor cell (CTC) clusters are both increasingly appreciated as highly metastatic precursors and virtually unexplored. Technologies are primarily designed to detect single CTCs and of...
