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Cohort profile: Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO)
The Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO) is a preconception, longitudinal cohort study that aims to study the effects of nutrition, lifestyle, and maternal mood pri...
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Open AccessLongitudinal assessment of antibiotic resistance gene profiles in gut microbiomes of infants at risk of eczema
While there is increasing knowledge about the gut microbiome, the factors influencing and the significance of the gut resistome are still not well understood. Infant gut commensals risk transferring multidrug-...
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Article
Open AccessComparison of microbiota and allergen profile in house dust from homes of allergic and non-allergic subjects- results from the GUSTO study
The prevalence of allergic diseases, such as asthma, allergic rhinitis, eczema and food allergy, has been increasing worldwide, as shown in a large number of studies, including the International Study of Asthm...
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Article
Open AccessEffects of infant weight gain on subsequent allergic outcomes in the first 3 years of life
The association between early weight gain and later allergic outcomes has not been well studied. We examined the relation between weight gain and the subsequent development of allergic outcomes in the first 36...
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Open AccessInternational consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem
Since mite allergens are the most relevant inducers of allergic diseases worldwide, resulting in significant morbidity and increased burden on health services, the International Collaboration in Asthma, Allerg...
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Article
Open AccessErratum to: Risk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement
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Open AccessPredictors of allergen sensitization in Singapore children from birth to 3 years
Immune responses in allergic diseases begin with allergen sensitization, which usually occurs in childhood. Allergen sensitization involves a complex interplay of genetic and environmental factors, and sensiti...
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Article
Open AccessRisk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement
One of the major concerns in the practice of allergy is related to the safety of procedures for the diagnosis and treatment of allergic disease. Management (diagnosis and treatment) of hypersensitivity disorde...
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Article
Open AccessThe use of inhaled corticosteroids in pediatric asthma: update
Despite the availability of several formulations of inhaled corticosteroids (ICS) and delivery devices for treatment of childhood asthma and despite the development of evidence-based guidelines, childhood asth...
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Article
Open AccessParticularities of allergy in the Tropics
Allergic diseases are distributed worldwide and their risk factors and triggers vary according to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but aspects of their prevalenc...
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Article
Open AccessWorld Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Vitamin D
The prevalence of allergic diseases is approximately 10 % in infants whose parents and siblings do not have allergic diseases and 20–30 % in those with an allergic first-degree relative. Vitamin D is involved in ...
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Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Erratum to: Severe Mycobacterial Diseases in a Patient with GOF IκBα Mutation Without EDA
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Open AccessWorld Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics
The prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10 % and reaches 20–30 % in those with an allergic first-degree relative. Intestinal microbiota ...
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Severe Mycobacterial Diseases in a Patient with GOF IκBα Mutation Without EDA
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Open AccessClinical phenotype and allergen sensitization in the first 2 years as predictors of atopic disorders at age 5 years
From a birth cohort of at-risk Asian infants, we prospectively investigated the role of early onset allergen sensitization and clinical phenotypes as risk factors for atopic disorders at the age of 5 years.
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Open AccessWorld Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Probiotics
Prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10% and reaches 20–30% in those with an allergic first-degree relative. Intestinal microbiota may mo...
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Article
A Comprehensive Review of Sensitization and Allergy to Soy-Based Products
Since 1943, cases of sensitization or allergy to soy-based formulas (SBFs) have been described without any consensus on their real prevalence. We identified the adjusted prevalence of IgE-mediated soy allergie...
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Open AccessMolecular analysis of infant fecal microbiota in an Asian at-risk cohort–correlates with infant and childhood eczema
Studies have suggested that selective microbial targets prevail in the fecal microbiota of infants with eczema. This study evaluated the composition of fecal microbiota of infants who developed eczema in the f...
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Open AccessA global survey of changing patterns of food allergy burden in children
While food allergies and eczema are among the most common chronic non-communicable diseases in children in many countries worldwide, quality data on the burden of these diseases is lacking, particularly in dev...
