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Open AccessCorrection: Corrigendum: Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration
Scientific Reports 6: Article number: 33830; published online: 22 September 2016; updated: 19 January 2017. This Article contains an error in panel C of Figure 4, where “WT” was incorrectly written as “E50K−tg...
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Open AccessMitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration
Mutations in optineurin (OPTN) are linked to the pathology of primary open angle glaucoma (POAG) and amyotrophic lateral sclerosis. Emerging evidence indicates that OPTN mutation is involved in accumulation of...
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Article
Interaction of Myocilin with γ-Synuclein Affects Its Secretion and Aggregation
Mutations in the gene encoding human myocilin are associated with some cases of juvenile and early-onset glaucoma. Glaucomatous mutations prevent myocilin from being secreted. The analysis of the defects assoc...
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Article
Alteration of cytoskeletal structure, integrin distribution, and migratory activity by phagocytic challenge in cells from an ocular tissue—The trabecular meshwork
The trabecular meshwork is a specialized tissue in the anterior chamber of the eye that regulates the aqueous humor outflow and controls the intraocular pressure. Cells in the trabecular meshwork are believed ...
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Article
Effects of chronic intracameral injections of chondroitin sulfate on cat eyes
The effect of chondroitin sulfate on the metabolism of trabecular meshwork was studied by repeatedly injecting a chondroitin sulfate solution into the anterior chamber of cat (experimental) eyes for 28–29 week...