4 Result(s)

Article

Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention

Memory consolidation requires astrocytic microdomains for protein recycling; but whether this lays a mechanistic foundation for long-term information storage remains enigmatic. Here we demonstrate that persist...

Beatrice Vignoli, Gabriele Sansevero, Manju Sasi… in Communications Biology (2021)

Article

Pharmacological inactivation of the prion protein by targeting a folding intermediate

Recent computational advancements in the simulation of biochemical processes allow investigating the mechanisms involved in protein regulation with realistic physics-based models, at an atomistic level of reso...

Giovanni Spagnolli, Tania Massignan, Andrea Astolfi, Silvia Biggi… in Communications Biology (2021)

Article

Erratum to: Neurobiology of local and intercellular BDNF signaling

Manju Sasi, Beatrice Vignoli, Marco Canossa… in Pflügers Archiv - European Journal of Phys… (2017)

Article

Neurobiology of local and intercellular BDNF signaling

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of secreted proteins. Signaling cascades induced by BDNF and its receptor, the receptor tyrosine kinase TrkB, link neuronal growt...

Manju Sasi, Beatrice Vignoli, Marco Canossa… in Pflügers Archiv - European Journal of Phys… (2017)