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Article
Open AccessDicer promotes genome stability via the bromodomain transcriptional co-activator BRD4
RNA interference is required for post-transcriptional silencing, but also has additional roles in transcriptional silencing of centromeres and genome stability. However, these roles have been controversial in ...
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Article
Levator ani and puborectalis muscle rupture: diagnosis and repair for perineal instability
Puborectalis muscle rupture usually arises from peri-partum perineal trauma and may result in anterior, middle compartment prolapses, posterior compartment prolapse which includes rectocele and rectal prolapse...
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Article
Development and internal validation of a diagnostic score for gastric linitis plastica
There is no consensual definition for gastric linitis plastica (GLP). We aim to construct a diagnostic score to distinguish this rare tumor from usual gastric adenocarcinomas.
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Article
Rectal advancement flap plus adipose lipofilling (RAFAL) for the treatment of rectourethral fistulas after radical prostatectomy
Rectourethral fistula (RUF) is a rare but significant complication after radical prostatectomy. Many different approaches have been used, but none of them has become the standard of care.
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Article
Levator ani repair by transvaginal approach
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Article
Colonic conduit prolapse after transanal total mesorectal excision (taTME)
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Article
Tailored therapy for different presentations of chronic pain after stapled hemorrhoidopexy
As stapled hemorrhoidopexy (SH) becomes more widely used, we see more patients with chronic postoperative anal pain after this surgery. Its presentation is variable and difficult to treat. The aim of our study...
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Article
Author’s reply to the letter of Doll et al.
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Article
The treatment of pilonidal disease: guidelines of the Italian Society of Colorectal Surgery (SICCR)
The Italian Society of Colorectal Surgery (SICCR.) has prepared clinical practice guidelines to help its members to optimize the treatment of pilonidal disease, a very common condition, especially among young ...
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Article
Harvesting dissipated energy with a mesoscopic ratchet
The search for new efficient thermoelectric devices converting waste heat into electrical energy is of major importance. The physics of mesoscopic electronic transport offers the possibility to develop a new g...
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Article
Detecting noise with shot noise using on-chip photon detector
The high-frequency radiation emitted by a quantum conductor presents a rising interest in quantum physics and condensed matter. However, its detection with microwave circuits is challenging. Here, we propose t...
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Article
Quantum tomography of an electron
Quantum tomography of individual electrons, which in principle yields complete knowledge of their quantum states, is demonstrated by initially preparing them in a well-controlled quantum state called a leviton.
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Article
Open AccessA two-atom electron pump
With the development of single-atom transistors, consisting of single dopants, nanofabrication has reached an extreme level of miniaturization. Promising functionalities for future nanoelectronic devices are b...
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Chapter
Single Dopant and Single Electron Effects in CMOS Devices
For the first time a state-of-the-art CMOS foundry (CEA-LETI-MINATEC) has been used to design silicon nanostructures with single or multiple gates dedicated to the study of single electron effects. The nanofab...
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Article
The Cold European Winter of 2005–2006 Assisted the Spread and Persistence of H5N1 Influenza Virus in Wild Birds
In January 2006, a major cold spell affected Europe, coinciding with an increase of H5N1 influenza virus detected in wild birds, mostly dead mute swans, starting along the River Danube and the Mediterranean co...
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Article
Optimizing electrode implantation in sacral nerve stimulation—an anatomical cadaver study controlled by a laparoscopic camera
Sacral nerve stimulation is the therapy of choice in patients with neurogenic faecal and urine incontinence, constipation and some pelvic pain syndromes. The aim of this study is to determine the best insertio...
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Article
Consensus conference on faecal incontinence
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Article
Comparison of transanal and external perineal ultrasonography
Anal endosonography with rotating endoprobes provides state-of-the-art imaging of sphincter integrity; however, the technique is not widely available and requires expensive equipment. Since pelvic anatomy per...
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Article
Outpatient proctological surgery: an analysis of 3725 cases
Outpatient proctological surgery is feasible if patients are carefully selected, if surgery is meticulous, if postoperative wound care is optimal, if postoperative analgesia is adequate and if a patients' con...
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Article
Rubber band ligation of hemorrhoids: relapse as a function of time
Rubber band ligation is a well established treatment of internal second-degree hemorrhoids. Up to now, the long-term results (>5 years) of this method have not been assessed. The aim of this study was to dete...