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    Article

    Nef: out and in?

    Lentiviral Nef protein has many functions in the evasion of host immune defenses. Another 'chink' in the host immune 'armor' has now been exposed by Nef's ability to inhibit immunoglobulin class switching.

    B Matija Peterlin in Nature Immunology (2006)

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    Hide, shield and strike back: how HIV-infected cells avoid immune eradication

  3. HIV escapes the immune system by hiding inside cells. In resting cells, blocks to the initiation and elongation of viral transcription have been proposed.

    ...
  4. B. Matija Peterlin, Didier Trono in Nature Reviews Immunology (2003)

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    Article

    Mutation in a winged-helix DNA-binding motif causes atypical bare lymphocyte syndrome

    Bare lymphocyte syndrome (BLS) is an autosomal recessive severe-combined immunodeficiency that can result from mutations in four different transcription factors that regulate the expression of major histocompa...

    Nada Nekrep, Nabila Jabrane-Ferrat, Hermann M. Wolf, Martha M. Eibl in Nature Immunology (2002)

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    Role of the X2 box in activated transcription from the DRA promoter in B cells

     We investigated the function of the evolutionary conserved X2 box in the promoter of the HLA-DRA gene from the human major histocompatibility complex (MHC) in resting and activated B cells. NF-X2, which contains...

    Niclas Setterblad, B. Matija Peterlin, G. Andersson in Immunogenetics (1997)

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    Article

    The function of the octamer-binding site in the DRA promoter

    The octamer binding site, which is located immediately upstream of the poorly conserved DRA TATA sequence, is important fof high levels of expression of this human major histocompatibility class II gene in B cell...

    Charles F. Voliva, Nabila Jabrane-Ferrat, B. Matija Peterlin in Immunogenetics (1995)

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    Article

    Transcriptional regulation of HLA class-II genes

    B. Matija Peterlin, Göran Andersson, Erika Lötscher, Sue Tsang in Immunologic Research (1990)

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    Article

    Methylation patterns of HLA-DR alpha genes in six mononuclear cell lines

    The relationship between DNA methylation and HLA-DR α gene expression was investigated in six mononuclear cell lines. RPMI-4265 (B cell) and HUT-78 (T cell) constitutively express HLA-DR. HL-60 (myelomonocyte) an...

    Yao Wang, B. Matija Peterlin in Immunogenetics (1986)