11 Result(s)
within
B. J. Casey
Psychiatry
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Article
Open AccessHeightened sensitivity to high-calorie foods in children at risk for obesity: insights from behavior, neuroimaging, and genetics
Pediatric obesity is a major public health concern. Genetic susceptibility and increased availability of energy-dense food are known risk factors for obesity. However, the extent to which these factors jointly...
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Article
Role of BDNF in the development of an OFC-amygdala circuit regulating sociability in mouse and human
Social deficits are common in many psychiatric disorders. However, due to inadequate tools for manipulating circuit activity in humans and unspecific paradigms for modeling social behaviors in rodents, our und...
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Article
Open AccessThe importance of social factors in the association between physical activity and depression in children
Physical activity is associated with reduced depression in youth and adults. However, our understanding of how different aspects of youth activities—specifically, the degree to which they are social, team-orie...
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Article
ADHD and cannabis use in young adults examined using fMRI of a Go/NoGo task
Children diagnosed with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for substance abuse. Response inhibition is a hallmark of ADHD, yet the combined effects of ADHD and regular substa...
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Article
Open AccessDyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically develo** children
Dyslexia and language impairment (LI) are complex traits with substantial genetic components. We recently completed an association scan of the DYX2 locus, where we observed associations of markers in DCDC2, KIAA0...
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Article
Open AccessSchizophrenia-risk variant rs6994992 in the neuregulin-1 gene on brain developmental trajectories in typically develo** children
The neuregulin-1 (NRG1) gene is one of the best-validated risk genes for schizophrenia, and psychotic and bipolar disorders. The rs6994992 variant in the NRG1 promoter (SNP8NRG243177) is associated with altered f...
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Article
Caloric Restriction Enhances Fear Extinction Learning in Mice
Fear extinction learning, the ability to reassess a learned cue of danger as safe when it no longer predicts aversive events, is often dysregulated in anxiety disorders. Selective serotonin reuptake inhibitors...
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Article
Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls
Genetic influences on behavior are complex and, as such, the effect of any single gene is likely to be modest. Neuroimaging measures may serve as a biological intermediate phenotype to investigate the effect o...
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Chapter
Dopamine and Glutamate in Attention Deficit Hyperactivity Disorder
Attention deficit hyperactivity disorder (ADHD) is a complex condition, thought to have multiple subtypes lurking within a broad, behaviorally defined phenotype, making it difficult to identify specific biolog...
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Chapter
Symposia
Goal: The goal of this symposium is to identify ‘state-of-the-art’ strategies for the use of antipsychotic medications in the management of children and adolescents with major psychiatric disorders. Learning o...
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Chapter
Functional Magnetic Resonance Imaging
Understanding the workings of the human brain is not an easy task. Cognitive functions unique to humans, such as language and its development, ultimately require noninvasive functional measurement of the human...
