13 Result(s)
within
B. J. Casey
English
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Article
Open AccessHeightened sensitivity to high-calorie foods in children at risk for obesity: insights from behavior, neuroimaging, and genetics
Pediatric obesity is a major public health concern. Genetic susceptibility and increased availability of energy-dense food are known risk factors for obesity. However, the extent to which these factors jointly...
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Open AccessUncertain threat is associated with greater impulsive actions and neural dissimilarity to Black versus White faces
Race is a social construct that contributes to group membership and heightens emotional arousal in intergroup contexts. Little is known about how emotional arousal, specifically uncertain threat, influences be...
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Article
Open AccessProcessing of Task-Irrelevant Race Information is Associated with Diminished Cognitive Control in Black and White Individuals
The race of an individual is a salient physical feature that is rapidly processed by the brain and can bias our perceptions of others. How the race of others explicitly impacts our actions toward them during i...
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Open AccessThe importance of social factors in the association between physical activity and depression in children
Physical activity is associated with reduced depression in youth and adults. However, our understanding of how different aspects of youth activities—specifically, the degree to which they are social, team-orie...
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Open AccessPrediction complements explanation in understanding the develo** brain
A central aim of human neuroscience is understanding the neurobiology of cognition and behavior. Although we have made significant progress towards this goal, reliance on group-level studies of the developed a...
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Open AccessDynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories
Fear can be highly adaptive in promoting survival, yet it can also be detrimental when it persists long after a threat has passed. Flexibility of the fear response may be most advantageous during adolescence w...
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Open AccessDyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically develo** children
Dyslexia and language impairment (LI) are complex traits with substantial genetic components. We recently completed an association scan of the DYX2 locus, where we observed associations of markers in DCDC2, KIAA0...
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Open AccessExtinction during memory reconsolidation blocks recovery of fear in adolescents
Adolescence is a time of intensified emotional experiences, during which anxiety and stress-related disorders peak. The most effective behavioral therapies for treating these disorders share exposure-based tec...
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Adolescent-specific patterns of behavior and neural activity during social reinforcement learning
Humans are sophisticated social beings. Social cues from others are exceptionally salient, particularly during adolescence. Understanding how adolescents interpret and learn from variable social signals can pr...
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Open AccessSchizophrenia-risk variant rs6994992 in the neuregulin-1 gene on brain developmental trajectories in typically develo** children
The neuregulin-1 (NRG1) gene is one of the best-validated risk genes for schizophrenia, and psychotic and bipolar disorders. The rs6994992 variant in the NRG1 promoter (SNP8NRG243177) is associated with altered f...
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Article
Caloric Restriction Enhances Fear Extinction Learning in Mice
Fear extinction learning, the ability to reassess a learned cue of danger as safe when it no longer predicts aversive events, is often dysregulated in anxiety disorders. Selective serotonin reuptake inhibitors...
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Article
Genes, brain, and behavior: Bridging disciplines
With excitement surrounding the publication of the human genome, scientists have set out to uncover the functions of specific genes. This special issue on Genes, Brain, and Behavior attempts to present researc...
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Article
COMT genotype influences prefrontal response to emotional distraction
Early studies of genetic effects on brain activity have been conducted to investigate primarily either the influence of polymorphisms in dopaminergic genes, especially the catechol-O-methyltransferase (COMT) gene...
