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Article
Reversible cerebral hyperperfusion syndrome after stenting of the carotid artery—Two case reports
Hyperperfusion syndrome can complicate carotid revascularization, be it endarterectomy or carotid artery stenting (CAS). Although extensive effort has been devoted to reducing the incidence of ischemic stroke ...
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Article
51jähriger Patient mit reversiblen Infarkt-ähnlichen EKG-Veränderungen
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Article
Endovascular catheter-delivered photodynamic therapy in an experimental response to injury model
The effectiveness of local endovascular photodynamic therapy (PDT) in preventing tissue hyperplasia was evaluated in a vascular injury model.
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Chapter and Conference Paper
Instrumente zur lokalen Applikation phototoxischer Substanzen
Die Angioplastie ist neben der medikamentösen Therapie zum wichtigsten Pfeiler der Behandlung von Herzkranzgefäßerkrankungen geworden. Der limitierende Faktor dieser Therapie ist die hohe Anzahl der Restenosen...
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Chapter and Conference Paper
Benzoporphyrinderivataufnahme in Kultivierten Myofibroblasten
Ein wesentliches Problem der perkutanen transluminalen Koronarangioplastie (PTCA) ist die hohe Rezidivstenoserate von 20–40% innerhalb der ersten sechs Monate (1). Die Proliferation von Zellen der arteriellen ...
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Chapter and Conference Paper
Applikationssysteme zur photodynamischen Prophylaxe der Rezidivstenose
Die PTCA ist nach ihrer klinischen Einführung im Jahr 1977 eine etablierte Methode zur Behandlung der symptomatischen arteriosklerotischen Gefäßverengung. Der dauerhafte Erfolg dieser Methode wird durch eine R...
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Article
Ultrastructural characteristics of cellular reaction after experimentally induced lesions in the arterial vessel
Restenosis after angioplasty occurs with an incidence of 20–50% and remains a major draw-back. Certain randomized studies suggest that a bigger post-angioplasty lumen predicts a better long-term outcome. Conve...
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Article
Interferon-con1 inhibitsc-myc gene expression in kaposi’s sarcoma cells
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Chapter and Conference Paper
Vergleich der in-vitro Aufnahme und Verteilung von liposomal gekoppelten Porphycenen (HEPn), acetylierten Porphycenen (ATPPn) und Hematoporphyrinderivaten (HPD) in kultiviertem humanem Plaquegewebe
Die Photodynamische Therapie (PDT) mit Porphycenen könnte durch ihre antiproliferativen Effekte zur Restenose-Prophylaxe Anwendung finden. Wir untersuchten die Kinetik verschiedener Aufbereitungsformen von neu...
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Chapter and Conference Paper
Photodynamische Therapie (PDT) in arteriellenGefäßsegmenten zur Prophylaxe der Zellproliferation nach Gefäßverletzung
Application of photosensitizers in endovascular Photodynamic therapy (PDT) might be a usefull approach to prevent restenosis by locally develo** a cytotoxic effects in porcine arterial vessel segments treate...
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Article
Fluorescence microscopic and histologic analysis of photosensitizer uptake in human atherosclerotic lesions
Photodynamic therapy (PDT) using haematoporphyrin derivatives (HPD) activated by laser light is a well-established treatment modality for superficial tumours. PDT might therefore have a role in the prevention ...
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Article
CSF shunt infections in children
The incidence of shunt infections and possible risk factors was investigated by chart analysis. From 1986 to 1989 350 shunt procedures were performed including 273 ventriculoperitoneal shunts and 75 ventriculo...
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Chapter and Conference Paper
Simpson-Atherektomie-Katheter
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Chapter
Detection of EGF receptor mRNA in human arteriosclerotic lesions
Growth factors and growth factor receptors are considered to be key elements in the pathogenesis of arteriosclerosis. To study the local expression of epidermal growth factor (EGF) receptor, plaque tissue spec...
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Chapter
Reduction of human plaque smooth muscle cell proliferative and migratory activities by calcium antagonists
Subendothelial invasion and subsequent proliferation of smooth muscle cells (SMCs) are considered to be basic determinants of plaque formation. Inhibitory effects on both cellular events may promise prevention...
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Chapter and Conference Paper
Screening potentiell anti-arteriosklerotisch wirksamer Substanzen anhand der Migrationsaktivität humaner Gefäßwandmyozyten im Zellkulturmodell
Die Einwanderung glatter Muskelzellen (SMC) aus der Media in den subendothelialen Raum wird im Rahmen der Plaqueformierung als wesentlicher, der Proliferation dieser Zellen vorgeschalteter pathogenetischer Pro...
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Chapter
Cellular alteration after experimental directional peripheral atherectomy
Cellular alterations play a pivotal role in restenosis after angioplasty. In order to investigate the early ultrastructural changes, directional atherectomy was performed in 20 pigs (body weight 25–34 kg) with...
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Chapter
Analysis of immunhistochemical differences of macrophages in arteriosclerotic biopsies from directional coronary atherectomy
Macrophages are an essential part of arteriosclerotic lesions. This study set out to analyse different functional and morphological features of macrophages. Therefore detection of specific cell markers in huma...
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Chapter
Lokalisation von basic Fibroblast Growth Factor (bFGF) in Normalgewebe und in Atherektomiegewebe arteriosklerotischer Gefäßwandläsionen
Der basische Fibroblasten-Wachstumsfaktor (basic Fibroblast Growth Factor, bFGF) gilt als einer der potentesten Faktoren für das Wachstum zahlreicher mesenchymaler, endokriner und neuraler Zellen sowie für die...
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Chapter
Immunohistochemical analysis of the extracellular matrix in tissue preparations from arteriosclerotic lesions
We analyzed immunohistochemically the distribution of the interstitial extracellular matrix components collagen I, III and V and the basement membrane (BM) constituents collagen IV, laminin, heparan sulfate pr...
