81 Result(s)

Article

Optimisation of vitamin D status in global populations

Vitamin D is important for musculoskeletal health. Concentrations of 25-hydroxyvitamin D, the most commonly measured metabolite, vary markedly around the world and are influenced by many factors including sun ...

N.C. Harvey, K.A. Ward, D. Agnusdei, N. Binkley, E. Biver… in Osteoporosis International (2024)

Article

Previous fracture and subsequent fracture risk: a meta-analysis to update FRAX

A large international meta-analysis using primary data from 64 cohorts has quantified the increased risk of fracture associated with a previous history of fracture for future use in FRAX.

J.A. Kanis, H. Johansson, E.V. McCloskey, E. Liu… in Osteoporosis International (2023)

Article

Effects of Vitamin D with Calcium and Associations of Mean 25-Hydroxyvitamin D Levels with 3-Year Change in Muscle Performance in Healthy Older Adults in the Boston STOP IT Trial

The purpose of this analysis was to assess whether (1) daily vitamin D₃ plus calcium supplementation vs. placebo or (2) the mean 25-hydroxyvitamin D [25(OH)D] level achieved during a 3-year trial was associated w...

B. Dawson-Hughes, J. Wang, K. Barger, L. Ceglia in Calcified Tissue International (2022)

Article

Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan

We describe the collection of cohorts together with the analysis plan for an update of the fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource comprises 2,138,428 p...

L. Vandenput, H. Johansson, E. V. McCloskey, E. Liu… in Osteoporosis International (2022)

Article

Bone material strength in normoglycemic and hyperglycemic black and white older adults

This cross-sectional study assessed cortical bone properties via impact microindentation in adults with normoglycemia, prediabetes, and early-stage T2D. Bone material strength index was stable across the glyce...

B. Dawson-Hughes, M. Bouxsein, K. Shea in Osteoporosis International (2019)

Article

Effects of a simple home exercise program and vitamin D supplementation on health-related quality of life after a hip fracture: a randomized controlled trial

To test the effects of vitamin D intervention and a simple home exercise program (HE) on health-related quality of life (HRQL) in the first 12 months after hip fracture.

K. Renerts, K. Fischer, B. Dawson-Hughes, E. J. Orav… in Quality of Life Research (2019)

Article

Issues of trial selection and subgroup considerations in the recent meta-analysis of Zhao and colleagues on fracture reduction by calcium and vitamin D supplementation in community-dwelling older adults

Zhao and colleagues are addressing an important question about the efficacy of calcium and vitamin D on fracture risk reduction among community-dwelling adults age 50+. However, we are concerned about four asp...

H.A. Bischoff-Ferrari, B. Dawson-Hughes, W.C. Willett in Osteoporosis International (2018)

Article

Increasing alkali supplementation decreases urinary nitrogen excretion when adjusted for same day nitrogen intake

We examined whether escalating doses of potassium bicarbonate (KHCO₃) supplements alter urinary nitrogen excretion expressed as a ratio to same day nitrogen intake (measure of muscle-protein breakdown). The ratio...

L. Ceglia, B. Dawson-Hughes in Osteoporosis International (2017)

Article

Gender-specific association between dietary acid load and total lean body mass and its dependency on protein intake in seniors

Diet-related mild metabolic acidosis may play a role in the development of sarcopenia. We investigated the relationship between dietary acid load and total lean body mass in male and female seniors age ≥ 60 ye...

A. M. Faure, K. Fischer, B. Dawson-Hughes, A. Egli… in Osteoporosis International (2017)

Article

The impact of the new National Bone Health Alliance (NBHA) diagnostic criteria on the prevalence of osteoporosis in the United States: supplementary presentation

We evaluated the prevalence of osteoporosis using the osteoporosis diagnostic criteria developed by the National Bone Health Alliance (NBHA), which includes qualified fractures, FRAX score in addition to BMD. ...

N. C. Wright, K. G. Saag, B. Dawson-Hughes, S. Khosla… in Osteoporosis International (2017)

Article

Conclusions stand firm with additional data

C. M. Weaver, B. Dawson-Hughes, J. M. Lappe, T. C. Wallace in Osteoporosis International (2017)