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Erratum: Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons
Correction to: Molecular Psychiatry advance online publication, 18 November 2014; doi:10.1038/mp.2014.143 Following publication of this paper, the authors noticed that cell line GM02036 was missing from Supple...
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Article
Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons
Psychiatric disorders have clear heritable risk. Several large-scale genome-wide association studies have revealed a strong association between susceptibility for psychiatric disorders, including bipolar disea...
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Open AccessA longitudinal pilot proton MRS investigation of the manic and euthymic states of bipolar disorder
Several lines of evidence implicate dysfunction in brain energy production as a key component of bipolar disorder. In particular, elevated brain lactate levels observed in this condition suggest a shift from a...
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Article
Chronic citicoline increases phosphodiesters in the brains of healthy older subjects: an in vivo phosphorus magnetic resonance spectroscopy study
Rationale: Phosphatidylcholine (PtdCho) in brain cell membranes decreases with age. Evidence from both animal and in vitro studies indicates that CDP-choline (citicoline) administration may increase phosphatidylc...
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Article
Vestibular control of sympathetic activity
It has been proposed that a vestibular reflex originating in the otolith organs and other body graviceptors modulates sympathetic activity during changes in posture with regard to gravity. To test this hypothe...
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Effect of viewing distance on the generation of vertical eye movements during locomotion
Vertical head and eye coordination was studied as a function of viewing distance during locomotion. Vertical head translation and pitch movements were measured using a video motion analysis system (Optotrak 30...
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Effects of midline medullary lesions on velocity storage and the vestibulo-ocular reflex
1. Crossing fibers were sectioned at the midline of the medulla caudal to the abducens nucleus in four cynomolgus monkeys. In two animals the lesions caused the time constant of horizontal and vertical per- an...
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Effects of lesions of the nucleus of the optic tract on optokinetic nystagmus and after-nystagmus in the monkey
1. The nucleus of the optic tract (NOT) and the dorsal terminal nucleus (DTN) of the accessory optic system were lesioned electrolytically or with kainic acid in rhesus monkeys. When lesions involved NOT and D...
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Eye movements induced by off-vertical axis rotation (OVAR) at small angles of tilt
Off-vertical rotation (OVAR) in darkness induced continuous horizontal nystagmus in humans at small tilts of the rotation axis (5 to 30 degrees). The horizontal slow eye velocity had two components: a mean vel...
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Motion perceptions induced by off-vertical axis rotation (OVAR) at small angles of tilt
Off-vertical axis rotation in darkness induces a perception of body motion which lasts as long as rotation continues. Perceived body motion is the combination of two simultaneous displacements. The most easily...
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Article
Nystagmus induced by stimulation of the nucleus of the optic tract in the monkey
1. The nucleus of the optic tract (NOT) was electrically stimulated in alert rhesus monkeys. In darkness stimulation evoked horizontal nystagmus with ipsilateral slow phases, followed by after-nystagmus in the...
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Article
Horizontal saccades induced by stimulation of the central mesencephalic reticular formation
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The central mesencephalic reticular formation (cMRF) was electrically stimulated in the alert monkey. Saccadi...
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Projections from the superior colliculus to a region of the central mesencephalic reticular formation (cMRF) associated with horizontal saccadic eye movements
Radioactive wheatgerm agglutinin (WGA) and horseradish peroxidase (HRP) were injected into portions of the mesencephalic reticular formation at sites where electrical stimulation induced either small or large ...
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Article
Velocity storage in the vestibulo-ocular reflex arc (VOR)
Vestibular and optokinetic nystagmus (OKN) of monkeys were induced by platform and visual surround rotation. Vision prolonged per-rotatory nystagmus and cancelled or reduced post-rotatory nystagmus recorded in...