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Article
Successful mobilization of peripheral blood stem cells after addition of ancestim (stem cell factor) in patients who had failed a prior mobilization with filgrastim (granulocyte colony-stimulating factor) alone or with chemotherapy plus filgrastim
This study assessed the ability of recombinant human stem cell factor (rHuSCF) to mobilize stem cells in 44 patients who had failed a prior mobilization (CD34+ yield 0.5–1.9 × 106/kg BW) with filgrastim-alone or ...
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Article
Engraftment syndrome: a common cause for rash and fever following autologous hematopoietic stem cell transplantation for multiple sclerosis
Autologous hematopoietic stem cell transplantation (HSCT) is currently being evaluated as a therapy for patients with progressive multiple sclerosis (MS) at risk of debilitating neurological impairment. While ...
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Article
Hospital attitudes: preliminary findings from donor action pilot projects
Purpose: As part of the Donor Action collaboration (Eurotransplant Foundation, The Netherlands; Organización National de Trasplantes, Spain; and The Partnership for Organ Donation, USA),...
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Article
T cell-depleted autologous hematopoietic stem cell transplantation for multiple sclerosis: report on the first three patients
Multiple sclerosis (MS) is a disease of the central nervous system characterized by immune-mediated destruction of myelin. In patients with progressive deterioration, we have intensified immunosuppression to t...
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Article
Changing patterns in organ donation in Eurotransplant, 1990–1994
Organ transplantation has become the treatment of choice for patients with end-stage organ failure and has led to progressive increases in the size of waiting lists over the past decade. Unfortunately, from 19...
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Article
Some contemporary ethical considerations related to organ transplantation
With the increasing number of transplantable organs and tissues, as well as improvements in transplantation results, has come a severe shortage of organ donors. Consequently, new ethical dilemmas, related to t...