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Open AccessRecognition and management of haemophagocytic lymphohistiocytosis on the ICU: a case series
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Use of proton transfer reaction time-of-flight mass spectrometry for the analytical detection of illicit and controlled prescription drugs at room temperature via direct headspace sampling
The first reported use of proton transfer reaction time-of-flight mass spectrometry (PTR-TOF-MS) for the detection of a range of illicit and prescribed drugs is presented here. We describe the capabilities of ...
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Open AccessOutcome of haematology patients admitted to intensive care in a tertiary centre: primary haematological diagnosis, recent chemotherapy and bone marrow transplantation are not associated with outcome
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Open AccessPatterns of infection and impact on outcome in haematology patients admitted to intensive care
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Proton transfer reaction mass spectrometry for the sensitive and rapid real-time detection of solid high explosives in air and water
Relying on recent developments in proton transfer reaction mass spectrometry (PTR-MS), we demonstrate here the capability of detecting solid explosives in air and in water in real time. Two different proton tr...
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An audit of timing of tracheostomy formation in neurosurgical patients: how long should we wait?
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Coagulopathy of liver disease does not increase the filter life during continuous renal replacement therapy
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Incidence of renal failure following orthotopic liver transplantation is lower in the Asian population
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Requirement for renal replacement therapy following orthotopic liver transplantation in adults is associated with prolonged mechanical ventilation and higher incidence of pneumonia
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Transaxillary endoscopic excision of benign breast lumps: a new technique
Benign breast lumps affect 10% of women in their lifetimes. Despite a favorable natural history enabling surveillance as an option, surgical excision continues to be popular. Avoiding a scar on the breast is a...
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Targeting cyclin D1, a downstream effector of INI1/hSNF5, in rhabdoid tumors
Rhabdoid tumors (RTs) are aggressive and currently incurable pediatric malignancies. INI1/hSNF5 is a tumor suppressor biallelically inactivated in RTs. Our previous studies have indicated that cyclin D1 is a key ...
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Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells
The role of Cox-2 in NSAID-induced apoptosis is debated. We studied the role of Cox-2 inhibition in apoptosis induced by a selective Cox-2 inhibitor, SC236 (a structural analogue of celecoxib) in two colon can...
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Intraocular cysticercosis simulating retinoblastoma in a 5-year-old child