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Open AccessHigh-spatial resolution epidemic surveillance of bacterial meningitis in the African meningitis belt in Burkina Faso
Despite improved surveillance capacities and WHO recommendations for subdistrict analysis, routine epidemic surveillance of acute bacterial meningitis in the African meningitis belt remains largely limited to ...
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Article
Spatial CART classification trees
We propose to extend CART for bivariate marked point processes to provide a segmentation of the space into homogeneous areas for interaction between marks. While usual CART tree considers marginal distribution...
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Article
Open AccessAn integrative modeling approach to the age-performance relationship in mammals at the cellular scale
Physical and cognitive performances change across lifespan. Studying cohorts of individuals in specific age ranges and athletic abilities remains essential in assessing the underlying physiological mechanisms ...
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Article
Influence Measures for CART Classification Trees
This paper deals with measuring the influence of observations on the results obtained with CART classification trees. To define the influence of individuals on the analysis, we use influence measures to propos...
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Article
Open AccessDrug sales data analysis for outbreak detection of infectious diseases: a systematic literature review
This systematic literature review aimed to summarize evidence for the added value of drug sales data analysis for the surveillance of infectious diseases.
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Book
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Chapter
A Model-Based Dimension Reduction Approach to Classification of Gene Expression Data
The monitoring of the expression profiles of thousands of genes have proved to be particularly promising for biological classification, particularly for cancer diagnosis. However, microarray data present major...
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Article
A Criterion Based on the Mahalanobis Distance for Cluster Analysis with Subsampling
A two-level data set consists of entities of a higher level (say populations), each one being composed of several units of the lower level (say individuals). Observations are made at the individual level, wher...
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Article
Yield stability in clones of Coffea canephora in the short and medium term: longitudinal data analyses and measures of stability over time
In perennial crops like coffee, genetic improvement efficiency is limited by several factors. These include determining the acceptable minimum observation period for yield traits, and also variation of the tra...
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Article
Spatial gradient of temperature and potential vegetation feedback across Europe during the late Quaternary
After the last glacial maximum (LGM; 18,000 years. bp) plants migrated onto areas made free by the retreating ice sheets. Pollen records document changes in ecosystems and are an important proxy for the reconstru...
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Article
Open AccessA novel method for measuring patients' adherence to insulin dosing guidelines: introducing indicators of adherence
Diabetic type 1 patients are often advised to use dose adjustment guidelines to calculate their doses of insulin. Conventional methods of measuring patients' adherence are not applicable to these cases, becaus...
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Article
Open AccessDesign of a graphical and interactive interface for facilitating access to drug contraindications, cautions for use, interactions and adverse effects
Drug iatrogeny is important but could be decreased if contraindications, cautions for use, drug interactions and adverse effects of drugs described in drug monographs were taken into account. However, the phys...
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Article
Asymptotic Distribution of Density-Dependent Stage-Grouped Population Dynamics Models
Matrix models are widely used in biology to predict the temporal evolution of stage-structured populations. One issue related to matrix models that is often disregarded is the sampling variability. As the samp...
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Article
Open AccessNormalization for triple-target microarray experiments
Most microarray studies are made using labelling with one or two dyes which allows the hybridization of one or two samples on the same slide. In such experiments, the most frequently used dyes are Cy 3 and Cy 5. ...
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Article
Open AccessAn iconic language for the graphical representation of medical concepts
Many medication errors are encountered in drug prescriptions, which would not occur if practitioners could remember the drug properties. They can refer to drug monographs to find these properties, however drug...
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Chapter and Conference Paper
Spatio-temporal Functional Regression on Paleoecological Data
The aim of this presentation is modeling the relationship between genetic diversity (represented by a positive number) and curves of temperature and precipitation. Our model links the genetic measure to the cl...
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Article
Estimation of the density of a clustered point pattern using a distance method
Distance-based methods use point-to-point distances or random-location-to-point distances in a cloud of points to estimate characteristics of the point pattern. One such characteristics is the density of point...
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Article
Open AccessA constrained polynomial regression procedure for estimating the local False Discovery Rate
In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (lFDR), which quantifies the evidence of a specific gene a...
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Chapter
Discriminant Analysis Based on Continuous and Discrete Variables
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Article
Simulation study of dissimilarity between point process
The spatial distributions of two species of tree result in a bivariate pattern. This pattern characterizes biological mechanism involved within a forest with the spatial localization of the trees. If we consid...
