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Article
Open AccessPlasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India
The mechanisms underlying the pathogenesis of cerebral malaria (CM) syndrome are not well understood. Previous studies have shown a strong association of inflammatory chemokines, apoptotic markers and angiogen...
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Article
Open AccessMacrophage migration inhibitory factor is associated with mortality in cerebral malaria patients in India
Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine implicated in the pathogenesis of a number of human diseases including inflammatory neurological diseases. Its role in the pathogenesi...
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Article
Open AccessAntibody responses to the merozoite surface protein-1 complex in cerebral malaria patients in India
Plasmodium falciparum infection causes cerebral malaria (CM) in a subset of patients with anti-malarial treatment protecting only about 70% to 80% of patients. Why a subset of malaria patients develops CM complic...
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Article
Open AccessPlasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India
Plasmodium falciparum in a subset of patients can lead to cerebral malaria (CM), a major contributor to malaria-associated mortality. Despite treatment, CM mortality can be as high as 30%, while 10% of survivors ...
