6 Result(s)
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Article
Open AccessSMYD3: a new regulator of adipocyte precursor proliferation at the early steps of differentiation
In obesity, adipose tissue undergoes a remodeling process characterized by increased adipocyte size (hypertrophia) and number (hyperplasia). The ability to tip the balance toward the hyperplastic growth, with ...
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Article
Open AccessCannabis use and atherosclerotic cardiovascular disease: a Mendelian randomization study
Association between cannabis use and development of atherosclerotic cardiovascular disease (ASCVD) is inconsistent and challenging to interpret, given existing study limitations.
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Article
Open AccessRandomly controlled drivers using minimally invasive sampling: assessment of drug prevalence in Western Switzerland over two time periods
According to the World Health Organization, road traffic injuries lead to 1.3 million deaths each year and represent the leading cause of death for young adults under 30 years old. The use of psychoactive subs...
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Article
Phenoty** of Human CYP450 Enzymes by Endobiotics: Current Knowledge and Methodological Approaches
Drug response is subject to an important within- and between-individual variability owing, mainly, to pharmacokinetic and pharmacodynamic factors. Pharmacokinetics includes metabolism by cytochrome P450 (CYP45...
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Article
Multiplex quantitative imaging of human myocardial infarction by mass spectrometry-immunohistochemistry
Simultaneous assessment of a panel of protein markers is becoming essential in order to enhance biomarker research and improve diagnostics. Specifically, postmortem diagnostics of early myocardial ischemia in ...
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Article
Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was performed to map elements in thin formalin-fixed paraffin-embedded tissue sections of two forensic cases with firearm and electrocuti...
