-
Article
Open AccessAssociation of apolipoprotein E genotypes, blood pressure, blood lipids and ECG abnormalities in a general population aged 85+
Several studies have linked apolipoprotein E (ApoE) ε4 allele with elevated cholesterol and blood pressure levels. Data on the association of APOE genotypes with blood pressure, lipids, atrial fibrillation and...
-
Article
Sex Differences in Cognitive Performance Among the Very Old--Mini-Mental State Examination in a Population Aged 85 Years and Over
We examined 553 persons aged 85 years or more, who comprised 92% of all 601 citizens of a Finnish city Vantaa. The Mini-Mental State Examination (MMSE), Index of Activities of Daily Living (ADL), and the Instr...
-
Article
A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1
We describe a novel variant of Alzheimer's disease (AD) in a Finnish pedigree with 17 affected individuals of both sexes in three generations. The disease is characterized by progressive dementia which is, in ...