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  1. No Access

    Article

    RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers

    Oncogenic alterations in the RAS/RAF/MEK/ERK pathway drive the growth of a wide spectrum of cancers. While BRAF and MEK inhibitors are efficacious against BRAFV600E-driven cancers, effective targeted therapies ar...

    Robert J. Nichols, Franziska Haderk, Carlos Stahlhut… in Nature Cell Biology (2018)

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    Article

    A diverse community of jute (Corchorus spp.) endophytes reveals mutualistic host–microbe interactions

    Endophytes are plant-associated microbes that live within plants as an integral part of the host metabolism and function. This study aimed to identify the molecular and physiological characteristics of both cu...

    Rifat Ara Najnin, Farhana Shafrin, Ahsan Habib Polash… in Annals of Microbiology (2015)

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    Article

    Structural, functional and molecular docking study to characterize GMI1 from Arabidopsis thaliana

    γ-irradiation and Mitomycin C Induced 1 (GMI1), is a member of the SMC-hinge domain-containing protein family that takes part in double stranded break repair mechanism in eukaryotic cells. In thi...

    Md. Rezaul Islam, Md. Ismail Hosen… in Interdisciplinary Sciences: Computational … (2013)

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    Article

    A computational prediction of structure and function of novel homologue of Arabidopsis thaliana Vps51/Vps67 subunit in Corchorus olitorius

    Vps mediated vesicular transport is important for transferring macromolecules trapped inside a vesicle. Although highly abundant, Vps shows tremendous sequence variation among diverse array of species. However...

    Aubhishek Zaman, Nurun Nahar Fancy in Interdisciplinary Sciences: Computational … (2012)