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    Article

    RNA sequencing-based transcriptomic profiles of embryonic lens development for cataract gene discovery

    Isolated or syndromic congenital cataracts are heterogeneous developmental defects, making the identification of the associated genes challenging. In the past, mouse lens expression microarrays have been succe...

    Deepti Anand, Atul Kakrana, Archana D. Siddam, Hongzhan Huang… in Human Genetics (2018)

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    Article

    Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract

    Although majority of the genes linked to early-onset cataract exhibit lens fiber cell-enriched expression, our understanding of gene regulation in these cells is limited to function of just eight transcription...

    Smriti A. Agrawal, Deepti Anand, Archana D. Siddam, Atul Kakrana… in Human Genetics (2015)