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  1. No Access

    Article

    RNA sequencing-based transcriptomic profiles of embryonic lens development for cataract gene discovery

    Isolated or syndromic congenital cataracts are heterogeneous developmental defects, making the identification of the associated genes challenging. In the past, mouse lens expression microarrays have been succe...

    Deepti Anand, Atul Kakrana, Archana D. Siddam, Hongzhan Huang… in Human Genetics (2018)

  2. Article

    Open Access

    The asparagus genome sheds light on the origin and evolution of a young Y chromosome

    Sex chromosomes evolved from autosomes many times across the eukaryote phylogeny. Several models have been proposed to explain this transition, some involving male and female sterility mutations linked in a re...

    Alex Harkess, **song Zhou, Chunyan Xu, John E. Bowers… in Nature Communications (2017)

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    Article

    Host-delivered RNAi-mediated root-knot nematode resistance in Arabidopsis by targeting splicing factor and integrase genes

    Root-knot nematodes (RKNs) are one of the most important biotic factors limiting crop productivity in many crop plants. The major RKN control strategies include development of resistant cultivars, application ...

    Anil Kumar, Atul Kakrana, Anil Sirohi, K. Subramaniam… in Journal of General Plant Pathology (2017)

  4. No Access

    Article

    Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract

    Although majority of the genes linked to early-onset cataract exhibit lens fiber cell-enriched expression, our understanding of gene regulation in these cells is limited to function of just eight transcription...

    Smriti A. Agrawal, Deepti Anand, Archana D. Siddam, Atul Kakrana… in Human Genetics (2015)