16 Result(s)

Chapter and Conference Paper

Performance of RCC Column Retrofitted with CFRP Wrap**s and the Wrap**s with Steel Angle-Batten Jacketing Under Blast Loading

Blasts and accidental explosions are being reported more frequently than before with grievous injuries and loss of lives and damage to the structure, increasing the concern of disaster management authority off...

Mohd Shariq, Mehtab Alam, Asif Husain in Recent Advances in Civil Engineering (2023)

Article

Jacketing with steel angle sections and wide battens of RC column and its influence on blast performance

Occurrence of extreme loadings on the structure caused by man-made or accidental explosions is not uncommon. Such loadings jeopardize the safety/stability of structure if the key load-carrying member(s) are da...

Mohd Shariq, Mehtab Alam, Asif Husain, S. M. Anas in Asian Journal of Civil Engineering (2022)

Chapter and Conference Paper

Vulnerability Assessment of a Reinforced Concrete Building Frame

Severe earthquakes are considered as a major hazard with a potential to cause substantial physical losses, economic losses and casualties. At the same time due to population inversion, new settlements are comp...

Adnan Hussain, Asif Husain, Md. Imteyaz Ansari in Smart Cities—Opportunities and Challenges (2020)

Article

Design and synthesis of butenolide-based amide derivatives as anti-inflammatory agents

Butenolide-based eighteen new amide derivatives (1–18) have been synthesized and evaluated for anti-inflammatory activity. The compounds 9, 17 and 4 exhibited significant in vivo inhibition of 84.69, 76.52 and 76...

Yakub Ali, Mohammad Sarwar Alam, Hinna Hamid, Asif Husain… in Medicinal Chemistry Research (2015)

Article

Synthesis, characterization, in vitro antimicrobial, and anthelmintic evaluations of 2-(4-chloro-3-methylphenoxy)-N′-[{5′-(substituted aryl)-furan-2′-yl}-methylidene]-acetohydrazides

In the present study, a novel series of 2-(4-chloro-3-methylphenoxy)-N′-[{5′-(substituted aryl)-furan-2′-yl}-methylidene]-acetohydrazides (4a–k) have been designed and synthesized with a new class of p-chloro-m-...

Munendra Mohan Varshney, Asif Husain, Versha Parcha in Medicinal Chemistry Research (2014)

Article

Essential aminoacid incorporated GABA–phthalimide derivatives: synthesis and anticonvulsant evaluation

A series of novel N-(2-(benzylamino)-1-substituted-2-oxoethyl)-4-(1,3-dioxoisoindolin-2-yl)butanamide derivatives were synthesized unifying the functionalized amino acid unit and GABA–phthalimide moiety with esse...

Priya Ahuja, Asif Husain, Nadeem Siddiqui in Medicinal Chemistry Research (2014)

Article

Synthesis, biological activities, and pharmacokinetics studies of a mutual prodrug of aceclofenac and paracetamol

An ester-based mutual prodrug (aceclofenac–paracetamol; AC-PR) was synthesized (one-pot method) with an aim of improving the therapeutic index through prevention of gastrointestinal irritation and bleeding tha...

Asif Husain, Priyanka Ahuja, M. Shaharyar, Aftab Ahmad… in Medicinal Chemistry Research (2014)

Article

Docking studies on butenolide derivatives as Cox-II inhibitors

To supplement hits from a high through put screening, a docking study on butenolides derivatives was performed as COX-II inhibitors. The fourteen ligands were docked inside the ligand-binding domain (LBD) of p...

Sukhbir Lal Khokra, Jyoti Monga, Asif Husain, Mohit Vij… in Medicinal Chemistry Research (2013)

Article

Pharmacophore modeling studies on N-hydroxyphenyl acrylamides and N-hydroxypyridin-2-yl-acrylamides as inhibitor of human cancer leukemia K562 cells

In order to understand the essential structural features for inhibitors of human cancer leukemia K562 cells, three-dimensional pharmacophore hypotheses were built on the basis of a set of inhibitors of human c...

Jyoti Monga, Sukhbir L. Khokra, Asif Husain in Medicinal Chemistry Research (2013)

Article

Synthesis and antimicrobial activity of bischalcone derivatives

Several bischalcones (2a–h and 5a–e) and flavones (3a–f) were synthesized and evaluated for their antimicrobial actions. Bischalcones were prepared by condensing 1,1′-(4,6-dimethyl-1,3-phenylene)diethanone (1) or...

Asif Husain, Aftab Ahmad, Ibraheem Ahmed I. Mkhalid… in Medicinal Chemistry Research (2013)

Article

Quinolone derivatives as antitubercular drugs

New chemotherapeutic drugs are the need to improve tuberculosis (TB) control particularly due to the emergence of multidrug-resistant strains and extensively drug-resistant strains of TB. These antitubercular ...

Mohammad Asif, Anees A. Siddiqui, Asif Husain in Medicinal Chemistry Research (2013)

Article

Studies on fused heterocyclic 3,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazoles: synthesis and biological evaluation

In this study, a series of 3,6-disubstituted-1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazoles (5a–t) were synthesized by condensing 4-amino-3-mercapto-(4H)-1,2,4-triazoles (4a–c) with different aromatic or aroyl acids t...

Asif Husain, Md. Arif Naseer in Medicinal Chemistry Research (2011)

Chapter and Conference Paper

Studies on a Mutual Prodrug of Sulfamethoxazole and Nalidixic acid

Asif Husain, M. S. Y. Khan in Understanding Biology Using Peptides (2006)

Article

Association of glycogen storage disease 1b and Crohn disease: results of a North American survey

Glycogen storage disease (GSD)-1b has been associated with neutropenia and abnormalities of neutrophil function. Many individuals with GSD-1b manifest chronic gastrointestinal inflammation. Our study was perfo...

Brian K. Dieckgraefe, Joshua R. Korzenik, Asif Husain… in European Journal of Pediatrics (2002)

Article

Association of glycogen storage disease 1b and Crohn disease: results of a North American survey

Glycogen storage disease (GSD)-1b has been associated with neutropenia and abnormalities of neutrophil function. Many individuals with GSD-1b manifest chronic gastrointestinal inflammation. Our study was per...

Brian K. Dieckgraefe, Joshua R. Korzenik, Asif Husain… in European Journal of Pediatrics (2002)