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Library preparation for highly accurate population sequencing of RNA viruses

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  1. Article

    Open Access

    Hsp90 shapes protein and RNA evolution to balance trade-offs between protein stability and aggregation

    Acquisition of mutations is central to evolution; however, the detrimental effects of most mutations on protein folding and stability limit protein evolvability. Molecular chaperones, which suppress aggregatio...

    Ron Geller, Sebastian Pechmann, Ashley Acevedo, Raul Andino… in Nature Communications (2018)

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