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Lrp5 regulation of bone mass and serotonin synthesis in the gut
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Article
Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts
A mouse model shows that osteoblast activating β-catenin mutations alone are sufficient to initiate the development of acute myeloid leukaemia acting through increased Notch signalling.
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Open AccessDifferential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells
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Article
Azithromycin Suppresses Activation of Nuclear Factor-kappa B and Synthesis of Pro-inflammatory Cytokines in Tracheal Aspirate Cells From Premature Infants
Nuclear factor-kappaB (NF-κB) plays a central role in regulating key proinflammatory mediators. The activation of NF-κB is increased in tracheal aspirate (TA) cells from premature infants develo** bronchopul...
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Article
Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method
The spectrophotometric/microplate reader assay method for glutathione (GSH) involves oxidation of GSH by the sulfhydryl reagent 5,5′-dithio-bis(2-nitrobenzoic acid) (DTNB) to form the yellow derivative 5′-thio...
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Article
Open AccessDifferential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells
Cigarette smoke mediated oxidative stress and inflammatory events in the airway and alveolar epithelium are important processes in the pathogenesis of smoking related pulmonary diseases. Previously, individual...
