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Article
Open AccessBiochemical and clinical studies of putative allergens to assess what distinguishes them from other non-allergenic proteins in the same family
Many protein families have numerous members listed in databases as allergens; however, some allergen database entries, herein called “orphan allergens”, are members of large families of which all other members...
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Article
Glutamate Dehydrogenase: Structure, Allosteric Regulation, and Role in Insulin Homeostasis
Glutamate dehydrogenase (GDH) is a homohexameric enzyme that catalyzes the reversible oxidative deamination of l-glutamate to 2-oxoglutarate. Only in the animal kingdom is this enzyme heavily allosterically regu...
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Article
Plant defensins and virally encoded fungal toxin KP4 inhibit plant root growth
Plant defensins are small, highly stable, cysteine-rich antimicrobial proteins that are thought to constitute an important component of plant defense against fungal pathogens. There are a number of such defens...