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Article
Open AccessSerum protein profiling reveals an inflammation signature as a predictor of early breast cancer survival
Breast cancers exhibit considerable heterogeneity in their biology, immunology, and prognosis. Currently, no validated, serum protein-based tools are available to evaluate the prognosis of patients with early ...
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Article
Open AccessNeuropilin-1 and placental growth factor as prognostic factors in metastatic breast cancer
Angiogenesis is crucial for tumor development, progression, and metastasizing. The most important regulator of angiogenesis is the vascular endothelial growth factor (VEGF) family, which is involved in multipl...
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Article
Open AccessPrevious radiotherapy improves treatment responses and causes a trend toward longer time to progression among patients with immune checkpoint inhibitor-related adverse events
Immune-related adverse events (irAEs) are frequently encountered by patients during immune checkpoint inhibitor (ICI) treatment and are associated with better treatment outcomes. The sequencing of radiotherapy...
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Article
Open AccessHigh baseline Tie1 level predicts poor survival in metastatic breast cancer
Angiopoietin growth factors (Angs) regulate angiogenesis and lymphangiogenesis by binding to the endothelial Tie2 receptor. Ang2 expression is elevated in tissue hypoxia and inflammation, which also induce cle...
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Article
Increased risk of certain second primary malignancies in patients treated for well-differentiated thyroid cancer
The objective was to evaluate the incidence of second primary malignancies (SPMs) in thyroid cancer patients compared to age- and gender-matched controls without thyroid cancer from the general population of ...