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  1. Article

    Open Access

    Recurrence Rates and Pharmacological Treatment for Hemorrhoidal Disease: A Systematic Review

    Hemorrhoidal disease (HD) is characterized by prolapse of the inflamed and bleeding vascular tissues of the anal canal. Although HD is associated with a high recurrence rate, there is a lack of understanding a...

    Varut Lohsiriwat, Parvez Sheikh, Robert Bandolon, Dong-Lin Ren in Advances in Therapy (2023)

  2. No Access

    Article

    Laser ablation of anal fistulae: a 6-year experience in a tertiary teaching hospital in Malaysia

    Several studies have investigated the role of laser ablation of anal fistulae in the European setting. However, long-term follow-up results following laser fistula ablations are not widely investigated and no ...

    Chu-Yik Tang, April Camilla Roslani in Lasers in Medical Science (2022)

  3. Article

    Open Access

    Comparison of post-operative bleeding incidence in laser hemorrhoidoplasty with and without hemorrhoidal artery ligation: a double-blinded randomized controlled trial

    The effectiveness of hemorrhoidal artery ligation supplementation in reducing the incidence of post laser hemorrhoidoplasty bleeding has not been investigated.

    Shu Yu Lim, Retnagowri Rajandram, April Camilla Roslani in BMC Surgery (2022)

  4. Article

    Pathological Complete Response After Neoadjuvant Therapy in Rectal Adenocarcinoma: a 5-Year Follow-up

    Neoadjuvant therapy is the gold standard treatment of locally advanced rectal cancer. It may induce complete sterilization of tumor cell and decreases its local recurrence rate. While 15–20% of patients were f...

    Yeen Chin Leow, April Camilla Roslani, Ruben Gregory Xavier in Indian Journal of Surgery (2021)

  5. Article

    Open Access

    LMTK3 confers chemo-resistance in breast cancer

    Lemur tyrosine kinase 3 (LMTK3) is an oncogenic kinase that is involved in different types of cancer (breast, lung, gastric, colorectal) and biological processes including proliferation, invasion, migration, c...

    Justin Stebbing, Kalpit Shah, Lei Cheng Lit, Teresa Gagliano, Angeliki Ditsiou in Oncogene (2018)

  6. Article

    Open Access

    Survival rates and predictors of survival among colorectal cancer patients in a Malaysian tertiary hospital

    Colorectal cancer is the third most commonly diagnosed malignancy and the fourth leading cause of cancer-related death globally. It is the second most common cancer among both males and females in Malaysia. Th...

    Bello Arkilla Magaji, Foong Ming Moy, April Camilla Roslani, Chee Wei Law in BMC Cancer (2017)

  7. No Access

    Article

    Heterogeneity in cancer cells: variation in drug response in different primary and secondary colorectal cancer cell lines in vitro

    Tumor heterogeneity may give rise to differential responses to chemotherapy drugs. Therefore, unraveling tumor heterogeneity has an implication for biomarker discovery and cancer therapeutics. To test this phe...

    Melanie Arul, April Camilla Roslani in In Vitro Cellular & Developmental Biology … (2017)

  8. No Access

    Article

    Financial burden of colorectal cancer treatment among patients and their families in a middle-income country

    In Malaysia, the healthcare system consists of a government-run universal healthcare system and a co-existing private healthcare system. However, with high and ever rising healthcare spending on cancer managem...

    Meram Azzani, April Camilla Roslani, Tin Tin Su in Supportive Care in Cancer (2016)

  9. No Access

    Article

    Pre-surgical Administration of Microbial Cell Preparation in Colorectal Cancer Patients: A Randomized Controlled Trial

    Disruption of normal gut function is a common side effect post abdominal surgery. It may result in reduced tolerance to oral nutrition and progress to postoperative ileus. Microbial cell preparation is benefic...

    Chun Khui Tan, Suraya Said, Retnagowri Rajandram, Zhiqiang Wang in World Journal of Surgery (2016)

  10. No Access

    Article

    The perceived cancer-related financial hardship among patients and their families: a systematic review

    The escalating health-care spending for cancer management has caused cancer patients to struggle further as a result of financial burden. This systematic review was carried out to investigate the prevalence of...

    Meram Azzani, April Camilla Roslani, Tin Tin Su in Supportive Care in Cancer (2015)

  11. No Access

    Article

    Culture of low passage colorectal cancer cells and demonstration of variation in selected tumour marker expression

    There is increasing evidence that a tumour comprises of heterogeneous population of cells. Thus, studying homogenous cell lines in vitro may yield results that are not reflective of the true situation in a tum...

    Melanie Arul, April Camilla Roslani, Colin Leong Liong Ng in Cytotechnology (2014)

  12. Article

    Open Access

    Advantage of using colonic washouts for Blastocystis detection in colorectal cancer patients

    There have been previous studies associating microorganisms to cancer and with our recent findings of Blastocytsis antigen having a higher in vitro proliferation of cancer cells strengthens the suspicion. Collect...

    Vinoth Kumarasamy, April Camilla Roslani, Kuppusamy Umah Rani in Parasites & Vectors (2014)

  13. Article

    Open Access

    Health-related quality of life among colorectal cancer patients in Malaysia: a study protocol

    Colorectal cancer is a major public health problem in Malaysia. However, it is also one of the most treatable cancers, resulting in significant numbers of survivors. Therefore, the impact of surviving treatmen...

    Bello Arkilla Magaji, Foong Ming Moy, April Camilla Roslani, Ismail Sagap in BMC Cancer (2012)