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    Article

    SUMOylation modulates the stability and function of PI3K-p110β

    Class I PI3K are heterodimers composed of a p85 regulatory subunit and a p110 catalytic subunit involved in multiple cellular functions. Recently, the catalytic subunit p110β has emerged as a class I PI3K isof...

    Ahmed El Motiam, Carlos F. de la Cruz-Herrera in Cellular and Molecular Life Sciences (2021)

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    Article

    Transcriptional repression of Bmp2 by p21Waf1/Cip1 links quiescence to neural stem cell maintenance

    The self renewal and long-term maintenance of neural stem cells (NSCs) is related to how quickly they pass through the cell cycle. Here the authors describe a new role for the cyclin-dependent kinase inhibitor...

    Eva Porlan, José Manuel Morante-Redolat in Nature Neuroscience (2013)