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Article

Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer

Abnormal regulation of β-catenin initiates an oncogenic program that serves as a main driver of many cancers. Albeit challenging, β-catenin is an attractive drug target due to its role in maintenance of cancer...

Anton Cheltsov, Natsuko Nomura, Venkata M. Yenugonda, Jatin Roper… in Scientific Reports (2020)