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Open AccessCorrection: Increased CpG methylation at the CDH1 locus in inflamed ileal mucosa of patients with Crohn disease
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Open AccessIncreased CpG methylation at the CDH1 locus in inflamed ileal mucosa of patients with Crohn disease
E-cadherin, a major actor of cell adhesion in the intestinal barrier, is encoded by the CDH1 gene associated with susceptibility to Crohn Disease (CD) and colorectal cancer. Since epigenetic mechanisms are suspec...
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Article
What is the Best Therapeutic Strategy for Metachronous Resectable Colorectal Liver Metastases After Adjuvant Oxaliplatin-Based Chemotherapy? A Multidisciplinary Inter-Group Survey
To report the current clinical practice of French physicians for metachronous resectable liver metastasis (LM) occurring after a FOLFOX adjuvant chemotherapy for primary cancer.
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Article
Mesh Repair in Crohn’s Disease: A Case-Matched Multicenter Study in 234 Patients
There are no specific guidelines for ventral hernia management in Crohn’s disease (CD) patients. We aimed to assess the risk of septic morbidity after mesh repair in CD.
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Article
What are the risk factors of failure of enhanced recovery after right colectomy? Results of a prospective study on 140 consecutive cases
Nausea and vomiting is the main cause of failure of enhanced recovery protocol (ERP) after right hemicolectomy.
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Article
Open AccessNORAD01-GRECCAR16 multicenter phase III non-inferiority randomized trial comparing preoperative modified FOLFIRINOX without irradiation to radiochemotherapy for resectable locally advanced rectal cancer (intergroup FRENCH-GRECCAR- PRODIGE trial)
Preoperative radiochemotherapy (RCT) is recommended in France prior to total mesorectal excision in patients with mid or low locally advanced rectal cancer (LARC) (cT3/T4 and/or N+) because it has been shown t...
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Article
Open AccessMulticenter phase III randomized trial comparing laparoscopy and laparotomy for colon cancer surgery in patients older than 75 years: the CELL study, a Fédération de Recherche en Chirurgie (FRENCH) trial
Several multicenter randomized controlled trials comparing laparoscopy and conventional open surgery for colon cancer have demonstrated that laparoscopic approach achieved the same oncological results while im...
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Article
The small height of an anastomotic colonic doughnut is an independent risk factor of anastomotic leakage following colorectal resection: results of a prospective study on 154 consecutive cases
The aim of this prospective study was to assess the influence of morphological characteristics of anastomotic doughnuts on the risk of anastomotic leakage (AL) after double-stapled colorectal anastomosis.
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Diagnosis and Treatment of Liver Metastases
Colorectal cancer is one of the leading causes of cancer death worldwide and in Asia. The most frequent cause of death in patients with colorectal cancer is due to liver metastases. Liver metastases can be det...
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Article
Sigmoid resection with primary anastomosis and ileostomy versus laparoscopic lavage in purulent peritonitis from perforated diverticulitis: outcome analysis in a prospective cohort of 40 consecutive patients
This prospective study aimed to compare outcomes after laparoscopic peritoneal lavage (LPL) and sigmoid resection with primary colorectal anastomosis (RPA).
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Article
Adjuvant Therapy in Combination with Resection of Colorectal Cancer Metastasis to the Liver or Lungs
Surgical resection is associated with prolonged survival for patients with limited lung or liver metastatic colorectal cancer. The benefit of resection of colorectal liver metastases is widely accepted. Howeve...
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Metastatic colorectal cancer outcome and fatty liver disease
Various factors are reported to affect the risk of local recurrence after resection of colorectal liver metastases. This article discusses the findings of a recent study that investigated the effect of fatty l...
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Methods to Improve Resectability of Hepatocellular Carcinoma
Liver resection is associated with prolonged survival in selected patients with hepatocellular carcinoma (HCC). Surgical resection of HCC may be decided on an individual basis according to the extent of the tu...
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Article
Neoadjuvant Chemotherapy Prior to Resection of Colorectal Liver Metastases
Surgery is the reference treatment of resectable colorectal liver metastases (CLM) as it is associated with 5-year survival rate as high as 50 % in selected patients. Unfortunately, most patients have too adva...
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Article
A laparoscopic approach to iterative ileocolonic resection for the recurrence of Crohn’s disease
Laparoscopy is a valuable approach to primary ileocecal resection for ileocolonic Crohn’s disease (CD). This study aimed to evaluate the feasibility of using laparoscopy for reoperation in the case of ileocolo...
