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  1. Article

    Open Access

    Comparative effectiveness of TNF inhibitor vs IL-6 receptor inhibitor as monotherapy or combination therapy with methotrexate in biologic-experienced patients with rheumatoid arthritis: An analysis from the CorEvitas RA Registry

    Randomized controlled trials (RCTs) in biologic-naïve rheumatoid arthritis (RA) patients with high disease activity and inadequate response/intolerance to methotrexate have shown interleukin-6 (IL-6) receptor ...

    Anthony Sebba, Clifton O. Bingham, Vivian P. Bykerk, Stefano Fiore in Clinical Rheumatology (2023)

  2. Article

    Open Access

    Efficacy and Safety of Ixekizumab with or Without Methotrexate in Biologic-Naïve Patients with Psoriatic Arthritis: 52-Week Results from SPIRIT-H2H Study

    In the SPIRIT-H2H (ClinicalTrials.gov: NCT03151551) trial in biologic-naïve patients with active psoriatic arthritis (PsA), ixekizumab (IXE) was superior to adalimumab (ADA) at week 24 in terms of achieving a ...

    Josef S. Smolen, Anthony Sebba, Eric M. Ruderman in Rheumatology and Therapy (2020)

  3. Article

    Open Access

    Efficacy and safety of the human anti-IL-1beta monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, phase II, dose-finding study

    Canakinumab is a fully human anti-interleukin IL-1beta monoclonal antibody, being investigated for the treatment of rheumatoid arthritis (RA). This multicenter, phase II, randomized, double-blind, placebo-cont...

    Rieke Alten, Juan Gomez-Reino, Patrick Durez in BMC Musculoskeletal Disorders (2011)

  4. No Access

    Article

    Optimizing Administration of Bisphosphonates in Women with Postmenopausal Osteoporosis

    Bisphosphonates have been approved in the US as oral medication for the treatment of osteoporosis for about 10 years. Efficacy data exists for fracture reduction for the commonly used oral bisphosphonates but ...

    Dr Paula J. Rackoff, Anthony Sebba in Treatments in Endocrinology (2005)